Medical School Histology: Images of compact bone

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Presentation transcript:

Medical School Histology: Images of compact bone Please subscribe Dr. Larry Johnson Texas A&M University

Observe/manipulate the images on your computer PowerPoint slides on YouTube VIBS Histology and at http://peer.tamu.edu/histology.asp

FUNCTIONS OF BONE SKELETAL SUPPORT LAND ANIMALS PROTECTIVE ENCLOSURE SKULL TO PROTECT BRAIN LONG BONE TO PROTECT HEMOPOIETIC CELLS

COMPACT BONE - SHAFT AND OUTER SURFACE OF LONG BONES Spongy Spongy

Vertebra Periosteum Compact bone Spongy bone Endosteum Endosteum Fibrous periosteum containing fibroblasts Bone Osteocyte in lacunae Osteoblasts lining bony trabeculae Endosteum Spongy bone

CELLS OF BONE OSTEOBLASTS - SECRETE OSTEOID - BONE OSTEOCYTE = EXPAND BONE BY APPOSITIONAL GROWTH OSTEOCYTE = OSTEOBLAST TRAPPED IN MATRIX OF BONE

EXTRACELLULAR MATRIX OF BONE SECRETED by POLARIZED OSTEOBLASTs CALCIFICATION - ADDS FIRMNESS, BUT PREVENTS DIFFUSION THROUGH MATRIX MATERIAL Osteocytes

EXTRACELLULAR MATRIX OF BONE FORMS LACUNAE AND CANALICULI -

EXTRACELLULAR MATRIX OF BONE FORMS LACUNAE AND CANALICULI - CAUSES THE NEED FOR NUTRIENTS TO PAST THROUGH THE MANY GAP JUNCTIONS BETWEEN OSTEOCYTES VIA CANALICULI

COMPACT BONE, REMODELING (Spongy bone)

COMPACT BONE, REMODELING (Spongy bone)

COMPACT BONE HAVERSIAN SYSTEMS - LAMELLAE OF BONE AROUND HAVERSIAN CANAL

Compact bone (ground cross section) Osteon or Haversian systems Compact bone (ground cross section) Volkmann’s canal Canaliculli Concentric lamellae Osteon/ Haversian systems Haversian canal Lacunae containing osteocyte Interstitial lamellae

Compact bone (ground cross section) Connecting adjacent osteons, perforating (Volkmann’s) canals provide communication for osteons and another source of microvasculature for the central canals of osteons (nutrients, blood, etc.). Volkmann’s canal

Download actual images at Bone 36726 – http://viewer.serenusview.com/LinkHandler.axd?LinkId=bfeae008-4430-49a9-8deb-200690e3f484

The End