Expression of Hoxa9 and Meis1a in spleen cells isolated from leukemic recipients of Hoxa9‐ and Meis1a‐transduced bone marrow cells. Expression of Hoxa9.

Slides:



Advertisements
Similar presentations
HOXA9 – AcuteMyeloidLeukemia. HOX Genes encode transcription factors
Advertisements

Marcello Arsura, Min Wu, Gail E Sonenshein  Immunity 
Colonic expression of DRA (downregulated in adenoma) mRNA in HLA-B27/β2M rat compared with normal control animal, as well as in patients with ulcerative.
A B D C E 5 kb 2 kb Copies per 1,000 GAPDH copies. UL US TRL
Increase in Elastin Gene Expression and Protein Synthesis in Arterial Smooth Muscle Cells Derived From Patients with Moyamoya Disease by Mari Yamamoto,
Supplementary figure 3 a b M 1 2 Probe: Unc5b 7 kb
Arterioscler Thromb Vasc Biol
Overexpression of PAI‐1 reverses the arsenite‐mediated effect on senescence Overexpression of PAI‐1 reverses the arsenite‐mediated effect on senescence.
Enhanced Vascularization of Cultured Skin Substitutes Genetically Modified to Overexpress Vascular Endothelial Growth Factor1  Dorothy M. Supp, Andrew.
Novel Cis Element for Tissue-Specific Transcription of Rat Platelet-Derived Growth Factor β-Receptor Gene by Yasunori Takata, Yutaka Kitami, Tomikazu Fukuoka,
Volume 6, Issue 1, Pages (January 1997)
by Madhu Gupta, Paul T. Mungai, and Eugene Goldwasser
The cyclin B1 promoter is accessible to restriction endonucleases in vivo. The cyclin B1 promoter is accessible to restriction endonucleases in vivo. Nuclei.
Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation by Michael J. Nemeth, David.
Elevated hepatic SULT1E1 activity in mouse models of cystic fibrosis alters the regulation of estrogen responsive proteins  Li Li, Charles N. Falany 
Upregulation of Cortactin Expression During the Maturation of Megakaryocytes by Xi Zhan, Christian C. Haudenschild, Yangson Ni, Elizabeth Smith, and Cai.
Calcium regulates ERK nuclear association, but not its activation.
Measurement of terminal restriction fragments (TRFs) in bone marrow cells from both parents and the G4 progeny. Measurement of terminal restriction fragments.
Nienke van der Stoep, James R Gorman, Frederick W Alt  Immunity 
Morphological analyses of peripheral blood and bone marrow cells isolated from leukemic mice. Morphological analyses of peripheral blood and bone marrow.
TRF2ΔBΔM induces apoptosis and senescence in the mouse liver.
by Kevin Oakley, Yufen Han, Bandana A
Consequences of T‐DNA insertion on SWP expression in swp mutant.
In Vivo Expression of Murine Platelet Glycoprotein Ibα
The gene encoding TP53INP1 is expressed in pancreatic endocrine cells A, B(A, B) Immunocytofluorescent staining of TP53INP1 (red) and insulin (green) in.
Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted complementary DNA library by Xianyong Ma, Tupur Husain,
by Xiaowu Zhang, and Ruibao Ren
D3: A Gene Induced During Myeloid Cell Differentiation of Linlo c-Kit+ Sca-1+ Progenitor Cells by Sarah R. Weiler, John M. Gooya, Mariaestela Ortiz, Schickwann.
Correction of a mouse model of sickle cell disease: lentiviral/antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells.
Volume 5, Issue 3, Pages (September 1996)
Isolation of genetically corrected recessive dystrophic epidermolysis bullosa (RDEB) epidermal stem cellsSingle cells were isolated from a mass culture.
Volume 7, Issue 6, Pages (December 1997)
The (4;11)(q21;p15) Translocation Fuses the NUP98 andRAP1GDS1 Genes and Is Recurrent in T-Cell Acute Lymphocytic Leukemia by Damian J. Hussey, Mario Nicola,
Expression of the Human Immunodeficiency Virus-Tat Gene in Lymphoid Tissues of Transgenic Mice Is Associated With B-Cell Lymphoma by Ramendra K. Kundu,
Volume 44, Issue 4, Pages (April 2006)
Interaction of HSV-1 Infected Peripheral Blood Mononuclear Cells with Cultured Dermal Microvascular Endothelial Cells: a Potential Model for the Pathogenesis.
Silencing in Yeast rDNA Chromatin
Volume 44, Issue 3, Pages (November 2011)
Volume 114, Issue 3, Pages (March 1998)
Fibrin and Collagen Differentially Regulate Human Dermal Microvascular Endothelial Cell Integrins: Stabilization of αv/β3 mRNA by Fibrin1  Xiaodong Feng,
Constitutive Bcl-2 Expression during Immunoglobulin Heavy Chain–Promoted B Cell Differentiation Expands Novel Precursor B Cells  Faith Young, Emiko Mizoguchi,
Volume 10, Issue 5, Pages (May 1999)
Volume 19, Issue 2, Pages (August 2003)
Isolation of genetically corrected recessive dystrophic epidermolysis bullosa (RDEB) epidermal stem cellsSingle cells were isolated from a mass culture.
MiR‐181s can induce immunoparalysis AGroups of mice were subjected to CLP, followed 2 days later by injection with agomir‐181d or agomir‐NC via tail vein.
James I Kim, I-Cheng Ho, Michael J Grusby, Laurie H Glimcher  Immunity 
Constitutive Bcl-2 Expression during Immunoglobulin Heavy Chain–Promoted B Cell Differentiation Expands Novel Precursor B Cells  Faith Young, Emiko Mizoguchi,
The Competitive Nature of HOXB4-Transduced HSC Is Limited by PBX1
Volume 10, Issue 8, Pages (April 2000)
Transplantation of IL-2–transduced murine bone marrow is associated with dose- dependent toxicity  Thomas Kühr, Oliver Bechter, Stephan Dirnhofer, Stephan.
UV Induces p21WAF1/CIP1 Protein in Keratinocytes Without p53
Histone deacetylase 1 protein depletion affects general histone acetylation and specific gene expression. Histone deacetylase 1 protein depletion affects.
Rpn11 overexpression inhibits TBSV recombination in plants.
Knockdown of Rpn11 inhibits TBSV accumulation in plants.
Effects of in vivo Nutlin‐3 treatment on CSC content of Numb− and Numb+ tumors Effects of in vivo Nutlin‐3 treatment on CSC content of Numb− and Numb+
Normal priming and expansion of functional T cells in the spleen during concurrent co‐infection Normal priming and expansion of functional T cells in the.
Ludovica Bruno, Hans Jörg Fehling, Harald von Boehmer  Immunity 
Volume 51, Issue 1, Pages (July 2013)
Volume 4, Issue 1, Pages (January 1996)
I.c.v.‐injected AβOs induce increased food intake, hypothalamic expression of orexigenic neuropeptides but no hypothalamic cell degeneration AAccumulated.
Overexpression of BTAK/Aurora-A in ovarian carcinoma.
Marcello Arsura, Min Wu, Gail E Sonenshein  Immunity 
T Cell Receptor δ Gene Rearrangement and T Early α (TEA) Expression in Immature αβ LineageThymocytes: Implications for αβ/γδ Lineage Commitment  Anne.
Volume 9, Issue 3, Pages (September 1998)
Volume 3, Issue 4, Pages (April 2001)
Reduced OXPHOS expression and increased UCP expression.
BORIS mRNA expression in DNMT deficient HCT116 cell lines.
Northern blot analysis of maspin in cancer cell lines and human tissues. Northern blot analysis of maspin in cancer cell lines and human tissues. A, HMECs.
Effect of hydrogen peroxide on survival and transcriptional activation of TFF1 in established cell lines from the following human tumor tissues: breast.
Volume 4, Issue 1, Pages (January 1996)
Presentation transcript:

Expression of Hoxa9 and Meis1a in spleen cells isolated from leukemic recipients of Hoxa9‐ and Meis1a‐transduced bone marrow cells. Expression of Hoxa9 and Meis1a in spleen cells isolated from leukemic recipients of Hoxa9‐ and Meis1a‐transduced bone marrow cells. Total spleen RNAs from nine leukemic mice (experiment 1) and one normal mouse (M) were analyzed by Northern hybridization to determine the expression of the retrovirally derived Hoxa9 (4.1 kb) and Meis1a (4.2 kb) transcripts. Autoradiographs are shown for membranes hybridized to probes specific for: Neor (top panel) showing both the expression of the 4.1 kb LTR‐driven Hoxa9‐bearing mRNA, as well as the internal pgk promoter‐driven 1.3 kb Neor mRNA; Hoxa9 (middle panel); and Meis1a (bottom panel). Mouse numbers are identified above the top panel. Exposure times were 18–24 h. The abnormal signals in lane 3 are secondary to poorly run RNA. The pgk promoter‐driven Neor in lane 9 is of abnormal size. This probably represents a splice variant as the integrated provirus is not rearranged in these cells (Figure 5C, lane 9). Each lane was loaded equally as determined by ethidium bromide staining of the membrane and by hybridization to an 18S rRNA probe (not shown). Evert Kroon et al. EMBO J. 1998;17:3714-3725 © as stated in the article, figure or figure legend