WHEN TO APPLY THE BRINDA REGRESSION CORRECTION APPROACH

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Presentation transcript:

WHEN TO APPLY THE BRINDA REGRESSION CORRECTION APPROACH Is there a clear biological rationale for a relationship between nutrient biomarker and inflammation? Yes Don’t know No Is the nutrient biomarker significantly correlated with AGP and CRP? BRINDA approach is not recommended Yes No BRINDA approach may be recommended BRINDA approach is not recommended

WHEN TO APPLY THE BRINDA APPROACH (Based on BRINDA papers) Recommended Not Recommended Serum ferritin (WRA/PSC) CRP and AGP Retinol binding protein (PSC) sTfR (WRA/PSC) AGP only Retinol binding protein (WRA) Let hold off on folate/B12 until published PSC= preschool age children WRA= women of reproductive (non-pregnant)