Renal and Extrarenal Complications of ADPKD: Facilitating Better Patient Care.

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This lecture was conducted during the Nephrology Unit Grand Ground by a Sub-intern under Nephrology Division, Department of Medicine in King Saud University.

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Presentation transcript:

Renal and Extrarenal Complications of ADPKD: Facilitating Better Patient Care

Program Goals

ADPKD: Genetics

ADPKD: Epidemiology

ADPKD: Clinical Aspects

ADPKD: Pathophysiology

Mechanism of PKD

ADPKD: Qualitative Differences

ADPKD: Diagnosis

Cyst Distribution

Current Ultrasound Diagnostic Criteria for ADPKD

ADPKD: Phenotypic Characteristics

Progressive Rise in Total Kidney Volume

Treatment Approaches to the Complications of ADPKD

Risk Factors for Renal Functional Deterioration

Clinical Characteristics to Monitor

Renal Treatment Approaches

Antihypertensives in ADPKD

Screening: An Unanswered Question

Treatment Targets in PKD

Novel Therapies in PKD*

Water as a Possible Treatment for PKD?

Novel Therapies Being Tested in Humans

Novel Therapies Being Tested in Humans (cont)

Novel Therapies in Animal Models

Closing Comments

Abbreviations

Abbreviations (cont)

References

References (cont)

References (cont)

References (cont)

References (cont)