Volume 145, Issue 1, Pages (July 2013)

Slides:



Advertisements
Similar presentations
American Gastroenterological Association Institute Technical Review on the Management of Acute Diverticulitis  Lisa L. Strate, Anne F. Peery, Ignacio.
Advertisements

Mice With Human Livers Gastroenterology
Covering the Cover Gastroenterology
Volume 139, Issue 1, Pages (July 2010)
Volume 143, Issue 5, Pages (November 2012)
Volume 105, Issue 3, Pages (May 2001)
Another Earth: Innate Lymphoid Cells and Intestinal Inflammation
Clinical Management of Patients With Acute Pancreatitis
Volume 137, Issue 1, Pages (July 2009)
Volume 132, Issue 3, Pages (March 2007)
Covering the Cover Gastroenterology
Evaluation and Management of End-Stage Liver Disease in Children
Regulation of Homeostasis and Inflammation in the Intestine
Volume 136, Issue 4, Pages (April 2009)
Volume 133, Issue 1, Pages (July 2007)
Is HCV Infection a Neurologic Disorder?
Outcomes Among Living Liver Donors
Lost in Inflammation: The Functional Conversion of Regulatory T Cells in Acute Hepatitis A Virus Infection  Tobias Boettler, Robert Thimme  Gastroenterology 
Unusual Cause of Elevated Liver Enzymes in a Female Patient
Ira J. Fox, Stephen C. Strom  Gastroenterology 
Gastroenterology 2011–2016: Looking Back and Forward
Making Sense of HDAC2 Mutations in Colon Cancer
Clinical Challenges and Images in GI
Unusual Case of an Upset Stomach
Volume 135, Issue 4, Pages (October 2008)
A Historical Perspective on Clinical Advances in Pancreatic Diseases
Volume 150, Issue 4, Pages (April 2016)
Lei Miao, XiangRong Chen, ZhiMing Huang  Gastroenterology 
American Gastroenterological Association Institute Technical Review on the Management of Acute Diverticulitis  Lisa L. Strate, Anne F. Peery, Ignacio.
Pulmonary Arterial Hypertension Associated With the Chinese Herb Indigo Naturalis for Ulcerative Colitis: It May Be Reversible  Mayu Nishio, Keiji Hirooka,
Volume 136, Issue 2, Pages (February 2009)
Clinical Challenges and Images in GI
Volume 141, Issue 5, Pages e9 (November 2011)
Volume 145, Issue 1, Pages (July 2013)
Colon Cancer: An Update and Future Directions
Volume 141, Issue 1, Pages e4 (July 2011)
Singling Out Intestinal Epithelial Stem Cells
Michael J. Williams, Andrew D. Clouston, Stuart J. Forbes 
Covering the Cover Gastroenterology
Laura Rotundo, Sushil Ahlawat  Gastroenterology 
Clinical Challenges and Images in GI
Volume 39, Issue 3, Pages (September 2003)
Reduced Mortality Rates Following Elective Percutaneous Liver Biopsies
Volume 139, Issue 1, Pages e2 (July 2010)
Volume 133, Issue 2, Pages (August 2007)
Volume 150, Issue 7, Pages (June 2016)
Ashwin N. Ananthakrishnan, David Lieberman  Gastroenterology 
Volume 148, Issue 3, Pages (March 2015)
Covering the Cover Gastroenterology
Volume 141, Issue 1, Pages (July 2011)
In Vitro Expansion and Transplantation of Intestinal Crypt Stem Cells
The Dawning of a New Editorial Board for Gastroenterology
Volume 149, Issue 6, Pages (November 2015)
Donor Race Does Not Predict Graft Failure After Liver Transplantation
Siddharth Singh, Matthew T. Howard, Konstantinos A. Papadakis 
Changing of the Guards: 2011–2016 Gastroenterology Team
Electronic Clinical Challenges and Images in GI
Volume 155, Issue 6, Pages (December 2018)
Volume 139, Issue 1, Pages (July 2010)
Volume 138, Issue 6, Pages (May 2010)
End-Stage Liver Disease in 2008: Finally a Glass Half Full
Reinvesting in US Biomedical Research—The Time is Now
Electronic Clinical Challenges and Images in GI
Neil D. Theise, Reichiro Kuwahara  Gastroenterology 
Controversies in Liver Transplantation for Hepatitis C
Genotype–Phenotype Relationships in Hepatocellular Carcinoma: p53 Inactivation Promotes Tumors With Stem Cell Features  Jean–Charles Nault, Jessica Zucman–Rossi 
Quiz Page September 2014 American Journal of Kidney Diseases
Digesting New Information About the Role of Trypsin in Pancreatitis
Volume 146, Issue 4, Pages (April 2014)
A Rare Tumor of the Liver With a Sudden Presentation
Presentation transcript:

Volume 145, Issue 1, Pages 253-254 (July 2013) Low Hepatocyte Repopulation From Stem Cells: A Matter of Hepatobiliary Linkage Not Massive Production  Neil D. Theise  Gastroenterology  Volume 145, Issue 1, Pages 253-254 (July 2013) DOI: 10.1053/j.gastro.2013.02.052 Copyright © 2013 AGA Institute Terms and Conditions

Figure 1 A, Label (BrdrU) retaining peribiliary hepatocytes (black nuclei) in murine acute acetaminophen toxicity represent the majority of label retaining cells in this injury model and probably derive from the smallest cholangiocytes of the canals of Hering (CoH; DAB stained pan-keratin, brown) to which they are connected (stain: hematoxylin counterstain; original magnification: ×40). B, Laminin staining in human liver is continuous around all ducts and ductules, but is interupted at the CoH:hepatocyte interface (arrow), a distinctive discontinuity that may relate to a specialized repopulating function of the CoH as a stem cell niche and be responsible for the unique ductular reactions that are seen in liver, but no other organ (DAB;stain: hematoxylin counterstain; original magnification: ×40). C, Laminin staining of human pancreas shows continuous basement membrane around all duct, acinar, and islet structures (*; DAB; stain: hematoxylin counterstain; original magnification: ×20). D, Laminin staining of human colon shows continuous basement membrane around all intestinal crypts (DAB; stain: hematoxylin counterstain; original magnification: ×10). (Laminin staining images provided by Christine Sempoux, Université Catholique de Louvain, Belgium.) Gastroenterology 2013 145, 253-254DOI: (10.1053/j.gastro.2013.02.052) Copyright © 2013 AGA Institute Terms and Conditions