Polyclonal Immunoglobulin Free Light Chain and Chronic Inflammation

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Presentation transcript:

Polyclonal Immunoglobulin Free Light Chain and Chronic Inflammation Frank A. Redegeld, PhD, Marco Thio, PhD, Tom Groot Kormelink, PhD  Mayo Clinic Proceedings  Volume 87, Issue 10, Pages 1032-1033 (October 2012) DOI: 10.1016/j.mayocp.2012.07.012 Copyright © 2012 Mayo Foundation for Medical Education and Research Terms and Conditions

FIGURE Immune disorders associated with increased immunoglobulin free light chains (FLC) and effector functions of immunoglobulin FLC leading inflammatory diseases via mast cell and neutrophil activation. COPD = chronic obstructive pulmonary disease; IBD = inflammatory bowel disease; IPF = idiopathic pulmonary fibrosis; RA = rheumatoid arthritis. Mayo Clinic Proceedings 2012 87, 1032-1033DOI: (10.1016/j.mayocp.2012.07.012) Copyright © 2012 Mayo Foundation for Medical Education and Research Terms and Conditions