Nicole C. Bouchard, MD, Mary Ann Howland, PharmD, Howard A

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Ischemic Stroke Associated With Use of an Ephedra-Free Dietary Supplement Containing Synephrine Nicole C. Bouchard, MD, Mary Ann Howland, PharmD, Howard A. Greller, MD, Robert S. Hoffman, MD, Lewis S. Nelson, MD Mayo Clinic Proceedings Volume 80, Issue 4, Pages 541-545 (April 2005) DOI: 10.4065/80.4.541 Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 1 Chemical structures of synephrine, phenylpropanolamine, amphetamine, and ephedrine. Mayo Clinic Proceedings 2005 80, 541-545DOI: (10.4065/80.4.541) Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 2 Non–contrast-enhanced computed tomograms of the head show multiple subacute infarctions (white arrows) in the left cerebellum (left, middle) and left thalamus (right). Mayo Clinic Proceedings 2005 80, 541-545DOI: (10.4065/80.4.541) Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 3 Magnetic resonance images of the brain show multiple subacute infarctions (white arrows) in the left cerebellum (left, middle), left thalamus (right, a), and left temporal lobe (right, b). Mayo Clinic Proceedings 2005 80, 541-545DOI: (10.4065/80.4.541) Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 4 Generic sympathomimetic phenylethylamine structure with activity alteration. See Table 1 for details. Mayo Clinic Proceedings 2005 80, 541-545DOI: (10.4065/80.4.541) Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions