CRISPR/Cas9 Clustered Regularly Interspaced Short Palindromic Repeats

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Presentation transcript:

CRISPR/Cas9 Clustered Regularly Interspaced Short Palindromic Repeats CRISPR Associated Protein 9

The mechanism Include CRISPR plasmid diagram rather than bacterial mechanism itself Lander , E. Cell. (2016)

The mechanism Include CRISPR plasmid diagram rather than bacterial mechanism itself https://sites.tufts.edu/crispr/genome-editing/

DSB repair pathways Ran, F.A. et al. Nature Protocols. (2013)

Applications Only include top 4 – cuts, deletions, labeling, regulation Adapted from Mali, P. et al. Nature. (2013)

The significance of CRISPR Research Potential for Biomedicine Contender for a Nobel Prize Potential for biomedicine Economist – crispr designing babies (some controversy), ... Nobel Prize Economist (August 2015)