Treating Headache Recurrence After Emergency Department Discharge: A Randomized Controlled Trial of Naproxen Versus Sumatriptan Benjamin W. Friedman,

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Presentation transcript:

Treating Headache Recurrence After Emergency Department Discharge: A Randomized Controlled Trial of Naproxen Versus Sumatriptan Benjamin W. Friedman, MD, MS, Clemencia Solorzano, RPh, David Esses, MD, Shujun Xia, MD, PhD, Michael Hochberg, MD, Niels Dua, MD, MS, Alan Heins, MD, MPH, Paul Sasso, MD, Polly E. Bijur, PhD, Richard B. Lipton, MD, E. John Gallagher, MD Annals of Emergency Medicine Volume 56, Issue 1, Pages 7-17 (July 2010) DOI: 10.1016/j.annemergmed.2010.02.005 Copyright © 2010 American College of Emergency Physicians Terms and Conditions

Figure 1 Diagrammatic representation of study protocol. Annals of Emergency Medicine 2010 56, 7-17DOI: (10.1016/j.annemergmed.2010.02.005) Copyright © 2010 American College of Emergency Physicians Terms and Conditions

Figure 2 Migraine without aura criteria. Annals of Emergency Medicine 2010 56, 7-17DOI: (10.1016/j.annemergmed.2010.02.005) Copyright © 2010 American College of Emergency Physicians Terms and Conditions

Figure 3 CONSORT flow diagram. Annals of Emergency Medicine 2010 56, 7-17DOI: (10.1016/j.annemergmed.2010.02.005) Copyright © 2010 American College of Emergency Physicians Terms and Conditions

Figure 4 Graphic depiction of change in pain scores between time of medication ingestion and 2 hours later. Larger pain scores signify greater pain. A, Migraine patients randomized to naproxen. B, Migraine patients randomized to sumatriptan. C, Nonmigraine patients randomized to naproxen. D, Nonmigraine patients randomized to sumatriptan. Annals of Emergency Medicine 2010 56, 7-17DOI: (10.1016/j.annemergmed.2010.02.005) Copyright © 2010 American College of Emergency Physicians Terms and Conditions