Cancer Immunosurveillance Caught in the Act

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Presentation transcript:

Cancer Immunosurveillance Caught in the Act Pedro Berraondo, Alvaro Teijeira, Ignacio Melero Immunity Volume 44, Issue 3, Pages 525-526 (March 2016) DOI: 10.1016/j.immuni.2016.03.004 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 Consequences of Immunosurveillance for Mutated Antigens in Human Cancer Flow chart of hallmark causes and consequences that connect defects in the DNA repair machinery of the tumor and the immune-mediated effects that determine prognosis, responsiveness to immunotherapy, and immunoediting. Mlecnik et al. have caught the consequences of immune surveillance in the act by following a series of MSI colon cancer patients and comparing them to MSS patients. Immunity 2016 44, 525-526DOI: (10.1016/j.immuni.2016.03.004) Copyright © 2016 Elsevier Inc. Terms and Conditions