In Search of the Ideal Pulmonary Blood Source for the Norwood Procedure: A Meta- Analysis and Systematic Review Vikas Sharma, MBBS, Salil V. Deo, MBBS,

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In Search of the Ideal Pulmonary Blood Source for the Norwood Procedure: A Meta- Analysis and Systematic Review Vikas Sharma, MBBS, Salil V. Deo, MBBS, Marianne Huebner, PhD, Joseph A. Dearani, MD, Harold M. Burkhart, MD The Annals of Thoracic Surgery Volume 98, Issue 1, Pages 142-150 (July 2014) DOI: 10.1016/j.athoracsur.2014.02.078 Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Flowchart demonstrates the method for selection of the included articles. (BT = Blalock-Taussig; RV-PA = right ventricle-to-pulmonary artery.) The Annals of Thoracic Surgery 2014 98, 142-150DOI: (10.1016/j.athoracsur.2014.02.078) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Forest plot demonstrates the relative risk for early mortality between the modified Blalock-Taussig shunt (MBTS) and the right ventricle-to-pulmonary artery (RV-PA) conduit for the stage 1 Norwood procedure. The squares depict the weight of each study, the horizontal lines depict the range of the individual relative risk, and the diamond depicts the pooled estimate with 95% confidence intervals (CIs). (RE = random effects.) The Annals of Thoracic Surgery 2014 98, 142-150DOI: (10.1016/j.athoracsur.2014.02.078) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Forest plot demonstrates the relative risks for interstage mortality between the modified Blalock-Taussig shunt (MBTS) and the right ventricle-to-pulmonary artery (RV-PA) conduit for the stage 1 Norwood procedure. The squares depict the weight of each study, the horizontal lines depict the range of the individual relative risks, and the diamond depicts the pooled estimate with 95% confidence intervals (CIs). (RE = random effects.) The Annals of Thoracic Surgery 2014 98, 142-150DOI: (10.1016/j.athoracsur.2014.02.078) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Forest plots demonstrate (A) total interventions (shunt and pulmonary arteries) between stage 1 and stage 2 for the modified Blalock-Taussig shunt (MBTS) and the right ventricle-to-pulmonary artery (RV-PA) conduit and (B) shunt interventions between stage 1 and stage 2 for the modified Blalock-Taussig shunt (MBTS) and the right ventricle-to-pulmonary artery (RV-PA) conduit. The squares depict the weight of each study, the horizontal lines depict the range of the individual relative risks, and the diamond depicts the pooled estimate with 95% confidence intervals (CIs). (RE = random effects.) The Annals of Thoracic Surgery 2014 98, 142-150DOI: (10.1016/j.athoracsur.2014.02.078) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 The Nakata index is shown in modified Blalock-Taussig shunt (MBTS; blue lines) and right ventricle-to-pulmonary artery (RV-PA; red lines) conduit groups. The Annals of Thoracic Surgery 2014 98, 142-150DOI: (10.1016/j.athoracsur.2014.02.078) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Forest plot demonstrates significant tricuspid regurgitation at the time of stage 2 between the modified Blalock-Taussig shunt (MBTS) and the right ventricle-to-pulmonary artery (RV-PA) conduit. The squares depict the weight of each study, the horizontal lines depict the range of the individual relative risks, and diamond depicts the pooled estimate with 95% confidence intervals (CIs). (RE = random effects.) The Annals of Thoracic Surgery 2014 98, 142-150DOI: (10.1016/j.athoracsur.2014.02.078) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions