Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté 

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The Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases  Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté  Cell Stem Cell  Volume 7, Issue 3, Pages 283-287 (September 2010) DOI: 10.1016/j.stem.2010.08.003 Copyright © 2010 Elsevier Inc. Terms and Conditions

Figure 1 Orphan Product Applications, Designations, and Marketing Approvals and Stem Cell-Based Product Orphan Designations (A) The quantities of orphan product applications, designations, and approvals collectively from 1983–2009 stratified by year class intervals. (B) Stem cell-based product orphan designations by year from 1983–2009. Cell Stem Cell 2010 7, 283-287DOI: (10.1016/j.stem.2010.08.003) Copyright © 2010 Elsevier Inc. Terms and Conditions