Could 3D bioprinted tissues offer future hope for microtia treatment?

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Could 3D bioprinted tissues offer future hope for microtia treatment? Daniel J. Thomas International Journal of Surgery Volume 32, Pages 43-44 (August 2016) DOI: 10.1016/j.ijsu.2016.06.036 Copyright © 2016 IJS Publishing Group Ltd Terms and Conditions

Fig. 1 3D-Bioprinting process in which a biologically active (bioink) is deposited into the shape of an ear structure. (A) human mesenchymal stem cells (hMSC) are collected from a patient, put into a growth medium and cultured into many millions of cells. (B) After a period of time in culture, these cells are added to a low viscosity hydrogel suspension consisting of gelatin and alginate. (C) Software control is used to position a high precision extruder in 3D. (D) This deposits the bioink in layers to form a cross linkable structure. (E) hMSCs post bioprinting show appropriate properties for initiating cartilage formation. International Journal of Surgery 2016 32, 43-44DOI: (10.1016/j.ijsu.2016.06.036) Copyright © 2016 IJS Publishing Group Ltd Terms and Conditions