Anti-diabetics Gymnema PH103.46

DEPARTMENT OF TECHNICAL EDUCATION ANDHRA PRADESH Name : B. Janaki Ramayya Designation : Sr. Lecturer Branch : Pharmacy Institute : GPW, Srikakulam Year/Semester : I. D.Pharm Subject : Pharmacognosy Subject code : Ph-103 Topic : Anti-diabetics Duration : 50 Mts Sub-topic : Gymnema Teaching Aids : Ppt, Photographs PH103.46 ER-91/PH-103/1 of 5

RECAP In the last class we learnt about : The Anti-diabetic monograph Pterocarpus PH103.46

OBJECTIVES On completion of this period you would be able to know about : The monograph of Anti-diabetic drug GYMNEMA SYLVESTRE PH103.46

GYMNEMA Synonym : Gudmar, Madhu nashini Biological Source : Consists of leaves of Gymnema sylvestre Family : Asclepiadaceae Fig.46.1 Gymnema PH103.46

GYMNEMA Geographical Source : Mainly found in India. Organoleptic Characters : Colour : Green Odour : Pleasant and aromatic Taste : Tasteless Fig.46.2 Gymnema PH103.46

GYMNEMA Organoleptic characters Size : 3-5 x1-2 cm Shape : Elliptic or ovate with acute or Acuminate apex Fig.46.1 Gymnema PH103.46

GYMNEMA Chemical constituents: Hentriacontane Penatriacontane Ptylin Alpha and beta Chlorophylls Resin Tartaric acid Fig.46.4 Gymnema PH103.46

GYMNEMA Chemical Constituents : Formic acid Butyric acid Mucilage Inositol d-quircitol Gymnemic acid Anthraquinone derivates PH103.46

GYMNEMA Standards: Ash : not more than 11.5%(w/w) Organic acids : not more than 5.5%(w/w) Alcohol soluble extractives : not more than 12.0%(w/w) PH103.46

GYMNEMA Chemical tests: Dilute solution anaesthetises sweet taste buds. Shake the leaves with water Copious foam which on addition of dilute Hydrochloric acid forms voluminous precipitate. PH103.46

GYMNEMA Uses: Antidiabetic (stimulates Insulin secretion ) Stimulant Stomachic Laxative Diuretic Substitute : Gymnema hirsutum PH103.46

Summary In this class we learnt about : Gymnema sylvestre Belongs to the family Asclepiadaceae Used as Anti-Diabetic Stimulates the secretion Of Insulin from pancreas. PH103.46

QUIZ Q 1. Gymnema belongs to the family b. Leguminosae c. Solanaceae a. Scrophulariaceae b. Leguminosae c. Solanaceae d. Asclepiadaceae PH103.46

QUIZ Q 2. Gymnema is used as b. Anti-septic c. Anti-diabetic a. Anti-pyretic b. Anti-septic c. Anti-diabetic d. Anti-viral PH103.46

Frequently asked Questions 1. Give an example for Anti-diabetic drug. Mention its Biological source, Morphological characters and Active constituents. (Mar./Apr’ 2004 ) Give two examples for Anti-diabetics. (March’ 2003 ) (December’ 2001) PH103.46