MR Airway Pressure Device Group Members Laura Sheehan Kevin Johnson Jon Cappel Noelle Simatic Client Dr. Victor Haughton Advisor Prof. Mitch Tyler

Chiari I Malformations http://www.chiariclinic.org

MR Background Tuner 90.7 104.1 B

Device

Normal Breathing (Holes Open) Valsalva (Holes Closed) Device Normal Breathing (Holes Open) Valsalva (Holes Closed) Vacuum Compressed Air

Validation Device Precision MR Compatibility Protocol Development Does the MR environment effect precision? Does scanning effect precision? MR Compatibility Does our device cause artifacts? Does our device degrade image quality? Protocol Development What’s the best way to perform this? Human/Animal Subjects Testing Final evaluation!!

Device Precision: Test Computer Controlled Flow Pump Transducer DAQ Trigger Measured ~240 Periods of Square flow waveform Outside room  With Setup in Side Room Inside Bore  Normal Setup During Scan Normal Setup during a scan

Device Precision: Results

Device Precision: Results SNR Measures Outside room: 40.99 Bore: 28.3 During Scan: 26.8 All less than 5% error Correlation Analysis Plotted Values against each other Pearson Coef (R=0.998) Slope of 1.01

MR Compatibility: Test Image 1 Image 2 Noise With Device Without Device Artifact

MR Compatibility: Preliminary Results Baseline With Device No obvious artifact but This noise level is unacceptable !!!!!

MR Compatibility: Future Work RF Z104 Top 100 Talk Radio DAQ Device NPR Shielding (copper) Control Room MR Suite

Future Work MR Compatibility Anesthetized Patient Prototype Additional Shielding Anesthetized Patient Prototype Protocol Development Human/Animal Subjects Testing IRB Approval Outreach Presentation Final Deliverables

as Chiari Patient “Little Suzie” Questions? Laura as Airway Team Member Noelle as Chiari Patient “Little Suzie” Kevin as Mitch Tyler Jon as Vic Haughton, M.D. Kevin as MR Tech