Analysis of Survival in 300 High-Risk Patients up to 2

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Analysis of Survival in 300 High-Risk Patients up to 2 Analysis of Survival in 300 High-Risk Patients up to 2.5 Years After Transapical Aortic Valve Implantation Axel Unbehaun, MD, Miralem Pasic, MD, PhD, Thorsten Drews, MD, Stephan Dreysse, MD, Marian Kukucka, MD, Roland Hetzer, MD, PhD, Semih Buz, MD The Annals of Thoracic Surgery Volume 92, Issue 4, Pages 1315-1323 (October 2011) DOI: 10.1016/j.athoracsur.2011.05.077 Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan-Meier-survival function for whole cohort of 300 patients. The Annals of Thoracic Surgery 2011 92, 1315-1323DOI: (10.1016/j.athoracsur.2011.05.077) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Kaplan-Meier-survival functions for different subgroups. (A) Survival in groups with different logistic EuroSCOREs. (B) Survival in groups with different Society of Thoracic Surgeons (STS) scores. (C) Survival in groups with different ages. (D) Survival in groups with different left ventricular ejection fraction (LVEF). (EuroSCORE = European System for Cardiac Operative Risk Evaluation.) The Annals of Thoracic Surgery 2011 92, 1315-1323DOI: (10.1016/j.athoracsur.2011.05.077) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 (A, left side) Box-whisker plots of age, logistic EuroSCORE, and STS score (A, right side) for all 300 patients. Box-whisker plots of age (B), logistic EuroSCORE (C), and STS score (D) for the first, second, and third consecutive 100 patients. p values from the Kruskal-Wallis-test and Mann-Whitney tests are given. (EuroSCORE = European System for Cardiac Operative Risk Evaluation; STS = The Society of Thoracic Surgeons; age is given in years; logistic EuroSCORE and STS score are given in %.) The Annals of Thoracic Surgery 2011 92, 1315-1323DOI: (10.1016/j.athoracsur.2011.05.077) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Q-Q plots of logistic EuroSCORE (A), STS score (B), and age (C) for all 300 patients indicating nongaussian distribution for all 3 parameters. (D) X-Y plot of both risk scores for all 300 patients and linear line fitting. (EuroSCORE = European System for Cardiac Operative Risk Evaluation; STS = The Society of Thoracic Surgeons; y=f(x) = regression equation; R2 = coefficient of determination.) The Annals of Thoracic Surgery 2011 92, 1315-1323DOI: (10.1016/j.athoracsur.2011.05.077) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions