Acetylcholine Receptor Binding Toxins

Slides:

Advertisements

Similar presentations

Changes In Protein Sequences Of the HIV-1 gp120 V3 Region In Non-Progressor Types Nicki S.Harmon Samantha M. Hurndon.

Advertisements

Undergraduate Exercises with Trp Cage Paula Evans, Chet Fornari, Jeff Hansen, Jennifer Inlow, Larry Merkle.

Neurotoxins in Snake Venom CobraGreen Mamba by Tim Reed, Katie Eaton, Cathy Peng, BettyLou Doern.

Sequence Alignment of CONSTANS-Like Proteins To understand the similarity of EpCOL and Arabidopsis CO and COL amino acid sequences, these protein sequences.

The construction of cells DNA or RNA Protein Carbohydrates Lipid etc.

Protein Functional Site Prediction The identification of protein regions responsible for stability and function is an especially important post-genomic.

The construction of cells DNA or RNA Protein Carbohydrates Lipid etc. 04.

Ion Channels. Cell membrane Voltage-gated Ion Channels voltage-gated because they open and close depending on the electrical potential across the membrane.

The construction of cells DNA or RNA Protein Carbohydrates Lipid etc

CHAPTER 25 TRACING PHYLOGENY. I. PHYLOGENY AND SYSTEMATICS A.TAXONOMY EMPLOYS A HIERARCHICAL SYSTEM OF CLASSIFICATION  SYSTEMATICS, THE STUDY OF BIOLOGICAL.

The construction of cells DNA or RNA Protein Carbohydrates Lipid etc

The construction of cells DNA or RNA Protein Carbohydrates Lipid etc.

Protein Synthesis Mrs. Harlin.

Multiple Alignment and Phylogenetic Trees Csc 487/687 Computing for Bioinformatics.

Protein Synthesis Occurs in 2 steps – Step 1: Transcription Taking DNA and transcribing it into RNA – Step 2: Translation Taking RNA and translating it.

PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1.

LESSON 8.4 SURFACE AREAS AND VOLUME OF SIMILAR SOLIDS Advanced Two Chapter 8 Volume and Similar Solids.

What our bodies are made of Chemistry of Cells. Nature of Matter All matter is made of atoms. Atoms consist of electrons, protons and neutrons. Molecules.

3DM: Protein Super-family Platforms 3DM Protein super-family data integration Tom van den Bergh Bio-Prodict.

Evolutionary pharmacology at the neuromuscular junction W. Rose.

Changes In Protein Sequences Of the HIV-1 gp120 V3 Region In Non-Progressor Types Nicki S.Harmon Samantha M. Hurndon LMU Department of Biology BIOL 368.

What is a macromolecule? There are four main types of biological molecules called macromolecules. The four types of macromolecules are carbohydrates, lipids,

Residue Sequence and Structure in the Re evaluation the Categorization of HIV Progression in Subjects Based on CD4 T cell Decline Rates Angela Garibaldi.

Molecular Evolution. Study of how genes and proteins evolve and how are organisms related based on their DNA sequence Molecular evolution therefore is.

FUNCTION FINDERS Discover how DNA sequences code for proteins with different roles and functions.

Neurotransmitters.

Using BLAST to Identify Species from Proteins

Dr. J AGDISH KAUR P.G.G.C.,Sector 11 Chandigarh

Alignment table: group 4

Supporting Figure S4 (A) (B) (C) LOC_Os03G04630 LOC_Os03G04640

Living By Chemistry SECOND EDITION

Four different segments of a DNA molecule are represented below.

Protein Alignments: Clues to Protein Function

Macromolecules: Proteins

Determining Relatedness

Structure of β2-bungarotoxin: potassium channel binding by Kunitz modules and targeted phospholipase action Peter D Kwong, Neil Q McDonald, Paul B Sigler,

Evidence of Evolution review

“Corination” of the proANP converting enzyme

Molecular Evolution.

Evidence and Phylogenetic trees

Prediction of protein structure

Sequences COURSE 3 LESSON 12-1

Evolutionary Reprograming of Protein-Protein Interaction Specificity

LMU Department of Biology

Determining Relatedness

Phosphopeptides identified harboring minimal binding motifs

Where would you draw the polyA tail in the gene above?______________

BIOLOGICAL ACTION OF DRUGS ON MEMBRANES

Each antibody binds to a specific antigen; an interaction similar to a lock and key.

Residue Sequence and Structure in the Re evaluation the Categorization of HIV Progression in Subjects Based on CD4 T cell Decline Rates Angela Garibaldi.

Immunological Comparisons

What DNA sequence codes for this chain of amino acids...?

Aim: Organic Compounds # 2 - Proteins

Similarities Differences

G protein coupled receptors

Structure prediction: Folding proteins by pattern recognition

The family of bone morphogenetic proteins

Volume 25, Issue 8, Pages e3 (August 2017)

Volume 2, Issue 1, Pages 1-4 (January 1994)

Volume 70, Issue 6, Pages (September 2006)

Amino acid sequence homology between XLMO-2 and the mouse, human and zebrafish homologs. Amino acid sequence homology between XLMO-2 and the mouse, human.

Alignment of the deduced amino acid sequences of the myosin light chain 2 (MLC2) proteins. Alignment of the deduced amino acid sequences of the myosin.

Chloe Jones, Isabel Gonzaga, and Nicole Anguiano

Phosphopeptides identified harboring minimal binding motifs

Four Levels of Protein Structure

Phylogenetic positions of the Fe hydrogenases of termite gut symbionts

Phylogenetic trees for fusion (F) and attachment (G) genes of selected HMPV isolates. Phylogenetic trees for fusion (F) and attachment (G) genes of selected.

Phylogenetic tree analysis of the Xenopus type III IFNs (A) with other known IFNs and the putative receptors (B) with relevant receptor families. Phylogenetic.

Presentation transcript:

Acetylcholine Receptor Binding Toxins Bungarus multicinctus: κ-bungarotoxin toxin source Link to BioQUEST Lesson Hypothesis: Similar functioning proteins that bind the ACh receptors will have similar amino acid sequences. Naja naja: α-cobra toxin source Results: *Overlay: α-cobra toxin a (Y), κ-bungarotoxin (B), Cobratoxin (G), Erabutoxin (O) ACh Receptor *Phylogenetic Tree: Conclusion: Four (4) toxins that affect ACh receptors were found to be closely related evolutionarily resulting in proteins that have structural areas of similarity in their amino acid sequences. *Associated Amino Acid Residue Sequences: α-bungarotoxin κ-bungarotoxin Cobratoxin Erabutoxin