Figure 1 Patients cured of HCV infection Figure 1 | Patients cured of HCV infection. a | Graph shows cured patients as percentage of patients treated with the indicated regimens. Year in brackets indicates when the treatment was introduced. b | Absolute number of patients in the USA and worldwide who were cured by 2013 (Ref. 6). About 600,000 patients worldwide were treated with sofosbuvir-containing regimens by the end of 2015. Of the 185 million people worldwide infected with HCV, only a minority have been diagnosed. Green bars represent patients infected with HCV and orange bars represent cured patients. Cure is defined as achieving sustained virologic response. DAA, direct acting antivirals; RBV, ribavirin. Rehermann, B. (2016) Advances in hepatitis C research and treatment Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2015.227