Distribution of peanut protein in the home environment

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Presentation transcript:

Distribution of peanut protein in the home environment Helen A. Brough, MSc, MRCPCH, Kerry Makinson, MSc, Martin Penagos, MSc, MD, Soheila J. Maleki, PhD, Hsiaopo Cheng, MS, Abdel Douiri, PhD, Alick C. Stephens, PhD, Victor Turcanu, PhD, Gideon Lack, MD, FRCPCH Journal of Allergy and Clinical Immunology Volume 132, Issue 3, Pages 623-629 (September 2013) DOI: 10.1016/j.jaci.2013.02.035 Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Within-home environmental peanut protein correlation. Correlations between peanut protein levels (in micrograms per gram) in maternal and paternal bed sheets (A; n = 38, rs = 0.864; 95% CI, 0.753-0.927; P < .001), infant's bed sheets and play areas (B; n = 32; rs = 0.862; 95% CI, 0.734-0.930; P < .001), maternal and infant's bed sheets (C; n = 34; rs = 0.844; 95% CI, 0.708-0.919; P < .001), and paternal and infant's bed sheets (D; n = 33; rs = 0.760; 95% CI, 0.564-0.875; P < .001) are shown. Axes are displayed in log scale. Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Time course of airborne peanut during peanut deshelling. The air sampling monitor was run for 10 minutes before, during, immediately after, and 30 and 60 minutes after deshelling peanuts at 1 cm and 1 m above the peanuts (n = 6). The y-axis is displayed in logarithmic scale. The LLQ (2.5 μg/m3) of the VPPE is depicted by a horizontal dotted line. Median peanut protein levels (in micrograms per cubic meter) are depicted during peanut deshelling at 1 cm versus 1 m above peanuts (P = .028*), with different peanut protein levels during peanut deshelling versus immediately after deshelling both at 1 cm and 1 m (P = .028*). Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Peanut protein levels (in micrograms per milliliter) in saliva (A; n = 6) and on hands (B; n = 6) before and 3 hours after consumption of 50 g of peanut. Median peanut protein levels (in micrograms per milliliter) are displayed before and after peanut consumption (P = .028*). The LLQ (0.025 μg/mL) is displayed as a horizontal dotted line. Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 Peanut protein levels (in micrograms per wipe) on 3 different table surfaces (granite, laminate, and wood) before and after a 0.5-mL peanut butter spike, water wipe, and vigorous detergent cleaning (n = 3). Median peanut protein levels (in micrograms per wipe) are displayed as a short horizontal line. The LLQ (0.2 μg per wipe) is displayed as a dotted line. Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 5 Peanut protein levels (in micrograms per gram of dust) in sofa covers (A) and pillows (B; n = 5 each) at baseline and after a machine detergent wash and then after peanut consumption and repeat machine detergent wash. Median peanut protein levels (in micrograms per gram of dust) are shown for each time point. The LLQ (0.5 μg/g dust) is displayed as a horizontal dotted line. Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E3 Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E4 Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E5 Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E6 Journal of Allergy and Clinical Immunology 2013 132, 623-629DOI: (10.1016/j.jaci.2013.02.035) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions