Suggested approach to patients with dabigatran-associated bleeding Suggested approach to patients with dabigatran-associated bleeding. aPCC, activated prothrombin complex concentrate; CRRT, continuous renal replacement therapy; HD, hemodialysis; PCC, prothrombin complex concentrate; rFVIIa, recombinant factor VIIa. Suggested approach to patients with dabigatran-associated bleeding. aPCC, activated prothrombin complex concentrate; CRRT, continuous renal replacement therapy; HD, hemodialysis; PCC, prothrombin complex concentrate; rFVIIa, recombinant factor VIIa. Felix Knauf et al. CJASN 2013;8:1591-1597 ©2013 by American Society of Nephrology