Outcomes with trisodium citrate 30% vs heparin as catheter-locking solution (all catheters) in patients on hemodialysis Variable TSC, n (%) Heparin, n (%) Relative risk (95% CI) p CRB 9 (6) 33 (23) 0.25 (0.12-0.52) <0.001 Death from CRB 5 0.96 (0.93-0.99) 0.028 Removal for any complication 42 (28) 66 (46) 0.57 (0.38-0.85) Exit-site infection 11 (7) 32 (22) 0.41 (0.20-0.81) 0.012 Removal for flow problems 27 (18) 29 (20) 0.92 (0.54-1.55) 0.75 Catheters treated with urokinase 69 (47) 63 (44) 1.11 (0.70-1.75) 0.72 Weijmer M et al. J Am Soc Nephrol 2005; Available at http://jasn.asnjournals.org.