The “dangers” of chronic proton pump inhibitor use

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Presentation transcript:

The “dangers” of chronic proton pump inhibitor use Rena Yadlapati, MD, MSHS, Peter J. Kahrilas, MD Journal of Allergy and Clinical Immunology Volume 141, Issue 1, Pages 79-81 (January 2018) DOI: 10.1016/j.jaci.2017.06.017 Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Mechanisms of potential risks associated with PPIs. Blue boxes represent effects that are observed. Green boxes represent effects that are weakly associated with PPI use. Pink boxes represent hypothetical effects that have not been reported or observed in association with PPI use. Black arrows are established linkages, whereas red arrows are proposed unproved links. ECL, Enterochromaffin-like; SBP, spontaneous bacterial peritonitis; SIBO, small intestinal bacterial overgrowth. Journal of Allergy and Clinical Immunology 2018 141, 79-81DOI: (10.1016/j.jaci.2017.06.017) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions