Urinary System: Outcome: I can explain why anti-diuretic hormone (ADH) is a critical part of the urinary system. Drill: What are differences between cortical nephrons and juxtamedullary nephrons?

Anti-Diuretic Hormone (ADH) Controls body water and solute concentration Produced by neurosecretory cells in the hypothalamus Water deprivation increases osmolarity of plasma which activates hypothalmic receptors to stimulate ADH release

Gland Secreted from the posterior pituitary gland The hypothalamus sends signals to the pituitary gland to secrete the hormone. Once hormone is secreted it goes to the kidney to put its purpose into effect.

Positive or Negative Feedback? Decreased water levels in body resulting in more ADH production- increased thirst- will reabsorb more water into the kidney Increased water levels result in a reduced ADH production telling the kidney to reabsorb less water.

Consequences of Disruption When ADH is inhibited, water will not be reabsorbed at the tubules and the body will produce dilute urine. Hyponatremia (not enough sodium (salt) in the body fluids outside the cells.) results in impaired water excretion. Incontinence- involuntary urination: Common in elderly people. Lack of ADH at night leads to bladder overfilling and thus urination.

Consequences of Disruption Continued… Increased ADH makes water remain inside your body, causing other chemicals in the blood such as salt may decrease. Too much may result in organs not functioning properly

Describe the feedback mechanism behind anti-diuretic hormone (ADH). Urinary System: Exit Ticket: Describe the feedback mechanism behind anti-diuretic hormone (ADH).