Using Fluorescence X-rays for Non-invasive Biopsy

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Presentation transcript:

Using Fluorescence X-rays for Non-invasive Biopsy Team members: Savannah Gill Kelvin Lin Mike McHugh Trey Reece Derric Williams Advisors: Dr. Frank Carroll Dr. Ed Donnelly Mr. Robert Traeger Mr. Gary Shearer

Objective Monochromatic X-rays Fire X-rays of only one energy (or wavelength) An alternative noninvasive method for biopsy Use fluorescent x-ray emissions from elements in tissue

Experiment Setup d R Specimen Monochromatic X-ray Collimator

Preliminary Experiments Kevex X-ray with Moly Tube Hands-On Experience Firing X-Ray Test for Beam Divergence Lanthanum Intensifier Screen Inverse Square Theorem Approximate Aperture Spacing

Selecting A Material Beer-Lambert Law Relationship between transmittance, mass attenuation coefficient, and material thickness. @30KeV μ (Fe) = 8.176 cm2/g μ (Al) = 1.128 cm2/g μ (Pb) = 30.32 cm2/g

Selecting a Material Cont. This means that using a thickness of 1cm, we could stop: 99.98% of the beam with Fe 67.64% of the beam with Al ~100% of the beam with Pb Since leaked X-Rays making it to the detector would increase our noise and could potentially make data analysis more difficult we decided to use…

Collimator Design Aluminum-Lead Sandwich Design

Collimator Design

Components Used Kevex X-Ray Lanthanum Intensifier Screen 2 Lead Sheet – 1.5 mm thick, 24X10 cm 2 Al Sheets- 25X11 cm

Components Used Cnt’d Drill Press Band Saw- 3/8 blade

Future Components Pb & Al Collimator Slimy Sally

Future Components Monochromatic X-Ray Translational Stage

Safety Precautions Radiation Safety Badges Lead Robes

Safety Precautions Latex Gloves Safety Goggles

Safety Precautions Handwashing Interlocking Doors Glass Wall “Laser In Use” Signs Scrap Bag

Work to Come X-Ray our collimator to evaluate hole quality Pick metal to block collimated beam Fire X-Ray through collimator and examine results. Write ImageJ script to automatically determine atomic composition.

Questions?