Anisocytosis and poikilocytosis

Slides:



Advertisements
Similar presentations
Structure and function of Haemoglobin
Advertisements

Chapter 13 The Red Blood Cell and Alterations in Oxygen Transport
Role of iron deficiency anemia in the propagation of beta thalassemia gene Usman, M., Moinuddin, M., Ahmed, S.A. (2011) Korean J Hematol 46: Microcytic.
HEMATOPOIETIC AND ANTI- ANEMIA AGENTS February 18, 2014 Thomas M. Guenthner, PhD 407D, MSB
Hemoglobinopathies Bara’a Bayan Eiad Ahlam Ahmad.
Mediterranean Anemia-Thalassemia
HEMOGLOBIN.
Hemoglobinopathies.
Course title: Hematology (1) Course code: MLHE-201 Supervisor: Prof. Dr Magda Sultan Outcome : The student will know : -The types of hemolytic anemias.
Haemoglobin structure Alpha- type Alpha- type Beta- type Beta- type Haem.
Haemoglobinopathies Ahmad Sh. Silmi Msc Haematology, FIBMS.
Fetal Hemoglobin. Definition: Is the main oxygen transport protein in the fetus during the last seven months of development in the uterus and in the newborn.
Population genetics is all about gene frequencies Evolution = a change in gene frequencies No change = genetic equilibrium = absence of evolution.
Chapter 11 The Red Blood Cell and Alterations in Oxygen Transport
TYPES OF HEMOGLOBINS & HEMOGLOBINOPATHIES
Laboratory diagnosis of Anemia
Hemoglobin and its types Presents to you by ABOUT DISEASE.CO TEAM.
MLAB 1415: Hematology Keri Brophy-Martinez
Sickle cell anaemia. ∞Its an inherited blood disorder that affects the production of haemoglobin that help carry oxygen around the blood. The body makes.
Nov.2008 Miss.TAHANI AL-SHEHRI Haemoglobin ( Hb) & anaemia.
1 Approach to Anemia in Children Dr.Hekmati Moghaddam.
Equilibrium Concept Review
Control of erythropoiesis, iron metabolism, and hemoglobin
Thalassemia Thalassemia is among the most common inherited disorders.
Anemias-continuation
Sickle cell Anaemia. What is it? The Hemoglobin protein in blood is effected This protein, which is different because of the iron found in it, is responsible.
By Dr. Manal Basyouni Dr. Manal Basyouni. Heme consists of a Porphyrin ring coordinated with iron. It is found mainly in hemoglobin but also present in.
Extreme RDW Differential
The Thalassemias.
Laboratory evaluation of erythrocyte RBC Haemoglobin Packed cell volume MCV MCH MCHC RDW Reticulocyte Blood film Quantitative description of erythropoiesis.
SICKLE CELL ANEMIA M.Murat Güçlü 224 EFE DEMİR – B.
microcytosis, hypochromia, anisocytosis normal RBC, WBC thrombocytosis
Hemtology Lecture 10. Definition the study of blood, the blood-forming organs, and blood diseases. Hematology includes Etiology Diagnosis Treatment Prognosis.
Variant types of Haemoglobinopathies
MLAB 1415: Hematology Keri Brophy-Martinez
HEMOGLOBIN. DR. Haroon Rashid. Lecture-29. Objectives Describe in detail the structure, synthesis, and catabolism of hemoglobin Explain the different.
HEMOGLOBIN (Hb) Structure of Hb The red, oxygen-carrying pigment in the red blood cells is hemoglobin, a protein with a molecular weight of 64,450.Hb is.
Sickle Cell Anemia Danny Gardner and Merline Maxi 1/28/10 Period 9/10.
Thalassemia A to Z Tim R. Randolph, PhD, MT(ASCP)
Hemoglobin Disorders Sickle cell anemia and Thalassemias Prepared by : Ahmed Ayasa Supervised by :Dr. Abdullateef Al Khateeb 1.
PRACTICE TEACHING ON THALASSEMIA. INTRODUCTION O Inherited blood disorder O an abnormal form of hemoglobin due to a defect through a genetic mutation.
Anaemias Polycythaemia.
What is the chemical reaction for CO 2 dissolving in H 2 O?
Professor A.M.A Abdel Gader MD, PhD, FRCP (Lond., Edin), FRSH (London) Professor of Physiology, College of Medicine King Khalid University Hospital Riyadh,
Mark D. Browning, M.D. March 10, 2016
Dr. Shumaila Asim Lecture # 4
Lec. 3 NOV 2016.
Dr. Shumaila Asim Lecture #6
Copyright © 2017 American Academy of Pediatrics.
Haemoglobin its structure, functions, types and abnormalities
Fetal Hemoglobin.
Anemia By: Dr Sunita Mittal.
BLOOD PHYSIOLOGY Lecture 2
Miss.Shuchismita Behera Miss.Sujata Dixit Dr.G.Bulliyya Dr.S.K.Kar
Hemoglobin estimation by Sahli's method (Sahli’s haemoglobinometer)
Dr. Shumaila Asim Lecture #6
Hemoglobinopathies in Pregnancy
CHROMOSOMES, ALLELES, GENES & MUTATIONS
Hemoglobin metabolism & diseases of hemoglobin
Haemoglobin structure & function
Transport of Oxygen 3% in dissolved form i. e. dissolved in plasma.
CLASSIFICATION OF ANEMIAS
Estimation of Hemoglobin
Biochemical Aspects of Thalasemia
Case Summary John a 4 year old boy ,complains of
BLOOD PHYSIOLOGY Lecture 2
BIOCHEMISTRY Gastroenterology & NUTRITION
Anemia case Group 16 Areej Faten Maha.
Beta thalasemia.
Inherited Disorders.
Presentation transcript:

Anisocytosis and poikilocytosis

Symptoms of Iron Deficiency Anemia Kiolonychia Angular cheil1osis

The Development of Iron Deficiency Anemia

Peripheral Blood Film Showing Iron deficiency Anemia

Dimorphic blood film in Iron deficiency anaemia responding to Iron therapy

Peripheral Blood Film Showing Megaloblastic Anemia

Haemoglobin

Synthesis of Haemoglobin

Types of Haemoglobin HbA ( Alpha2 Beta2) HbA2 ( Alpha2 Delta2) Hb A1c HbF ( Alpha2 Gamma2) Gower I ( Zeta2 Eeta2) Gower II (Alpha2 Eeta2) Met Hemoglobin

Reactions of Hemoglobin Combine with O2 Combine with CO2 Combine with CO Combine with NO Combine with H Ions

Inherited Disorders of Hemoglobin Hemoglobinopathies e.g Sickle cell anemia Thalasemias e.g Alpha and Beta