Median NT-proBNP levels (pg/mL) by GFR and 60-day survival Admission GFR Dead by 60 d Alive at 60 d p <60 mL/min/1.73m2 5565 2528 0.001 >60 mL/min/1.73m2 1423 163 <0.001 NT-proBNP=N-terminal brain-type natriuretic peptide GFR=glomerular filtration rate Anwaruddin S et al. J Am Coll Cardiol 2005; available at http://www.sciencedirect.com.
Sensitivity and specificity for diagnosing HF, by NT-proBNP cut points and renal function Parameter GFR <60 mL/min/1.73 m2 GFR >60 mL/min/1.73 m2 (age >50 y) GFR >60 mL/min/1.73 m2 (age <50 y) Cut point (pg/mL) >1200 >900 >450 Sensitivity (%) 89 85 Specificity (%) 72 88 NT-proBNP=N-terminal brain-type natriuretic peptide GFR=glomerular filtration rate Anwaruddin S et al. J Am Coll Cardiol 2005; available at http://www.sciencedirect.com.