Pitfalls in the dermoscopic diagnosis of amelanotic melanoma

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Presentation transcript:

Pitfalls in the dermoscopic diagnosis of amelanotic melanoma Maria A. Pizzichetta, MD, Vincenzo Canzonieri, MD, Samuele Massarut, MD, Tanja Baresic, MD, Eugenio Borsatti, MD, Scott W. Menzies, PhD Journal of the American Academy of Dermatology Volume 62, Issue 5, Pages 893-894 (May 2010) DOI: 10.1016/j.jaad.2009.09.036 Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 A, A 4-mm thick nodular malignant melanoma on the back of a 55-year-old man. Note the pink symmetrical nodule, associated with some whitish-yellow areas and a dotted trace of pigment B, The dermoscopic image of the same melanoma revealed a polymorphous vascular pattern characterized by milky red/pink areas (blue arrows), more than one shade of pink, linear irregularly sized vessels (black arrows), ranging from very subtle and coiled to large and aneurismatic, and large, slightly blurred arborizing vessels (green arrows). In addition, large and irregularly round, whitish-yellow areas, suggesting milia-like structures (red arrows), ovoid areas of depigmentation (star), and a small globule-like pigmented structure (yellow arrow) can be seen within the diffuse pinkish pigmentation. (Original magnifications: A, ×10; B, ×20.) Journal of the American Academy of Dermatology 2010 62, 893-894DOI: (10.1016/j.jaad.2009.09.036) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 A, Large, confluent dermal nodules of amelanotic melanoma cells and central well defined necrotic areas (blue arrows). B, Details of neoplastic cytotype. (Hematoxylin–eosin stain; original magnifications: A, ×10; B, ×25.) Journal of the American Academy of Dermatology 2010 62, 893-894DOI: (10.1016/j.jaad.2009.09.036) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions