Eosinophil cationic protein and histamine after intestinal challenge in patients with cow's milk intolerance Ulf Bengtsson, MD, PhDa, Tina W. Knutson,

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Eosinophil cationic protein and histamine after intestinal challenge in patients with cow's milk intolerance Ulf Bengtsson, MD, PhDa, Tina W. Knutson, MDb, Lars Knutson, MD, PhDc, Anders Dannaeus, MD, PhDb, Roger Hällgren, MD, PhDd, Staffan Ahlstedt, PhDe,f Journal of Allergy and Clinical Immunology Volume 100, Issue 2, Pages 216-221 (August 1997) DOI: 10.1016/S0091-6749(97)70227-6 Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 1 Rates of histamine secretion into isolated jejunal segment in five patients. A, Individual secretion rates after challenge with milk as antigen (arrow). All five patients responded with increased secretion after challenge. B, Comparison of secretion after challenge (arrow) with three antigens: milk, casein, and whey (mean ± SEM). Only full cow's milk induced a significant increase in secretion (*p < 0.05). C, Comparison of secretion in patients and control subjects after challenge with milk (mean ± SEM; *p < 0.05). Journal of Allergy and Clinical Immunology 1997 100, 216-221DOI: (10.1016/S0091-6749(97)70227-6) Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 1 Rates of histamine secretion into isolated jejunal segment in five patients. A, Individual secretion rates after challenge with milk as antigen (arrow). All five patients responded with increased secretion after challenge. B, Comparison of secretion after challenge (arrow) with three antigens: milk, casein, and whey (mean ± SEM). Only full cow's milk induced a significant increase in secretion (*p < 0.05). C, Comparison of secretion in patients and control subjects after challenge with milk (mean ± SEM; *p < 0.05). Journal of Allergy and Clinical Immunology 1997 100, 216-221DOI: (10.1016/S0091-6749(97)70227-6) Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 1 Rates of histamine secretion into isolated jejunal segment in five patients. A, Individual secretion rates after challenge with milk as antigen (arrow). All five patients responded with increased secretion after challenge. B, Comparison of secretion after challenge (arrow) with three antigens: milk, casein, and whey (mean ± SEM). Only full cow's milk induced a significant increase in secretion (*p < 0.05). C, Comparison of secretion in patients and control subjects after challenge with milk (mean ± SEM; *p < 0.05). Journal of Allergy and Clinical Immunology 1997 100, 216-221DOI: (10.1016/S0091-6749(97)70227-6) Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 2 Rates of ECP secretion into isolated jejunal segment in five patients. A, Individual increase in ECP secretion in all five patients after challenge (arrow). B, Comparison of ECP secretion after challenge (arrow) with the three antigens: milk, casein, and whey (mean ± SEM). C, Comparison of secretion in patients and control subjects after challenge with milk (mean ± SEM; *p < 0.05). Journal of Allergy and Clinical Immunology 1997 100, 216-221DOI: (10.1016/S0091-6749(97)70227-6) Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 2 Rates of ECP secretion into isolated jejunal segment in five patients. A, Individual increase in ECP secretion in all five patients after challenge (arrow). B, Comparison of ECP secretion after challenge (arrow) with the three antigens: milk, casein, and whey (mean ± SEM). C, Comparison of secretion in patients and control subjects after challenge with milk (mean ± SEM; *p < 0.05). Journal of Allergy and Clinical Immunology 1997 100, 216-221DOI: (10.1016/S0091-6749(97)70227-6) Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 2 Rates of ECP secretion into isolated jejunal segment in five patients. A, Individual increase in ECP secretion in all five patients after challenge (arrow). B, Comparison of ECP secretion after challenge (arrow) with the three antigens: milk, casein, and whey (mean ± SEM). C, Comparison of secretion in patients and control subjects after challenge with milk (mean ± SEM; *p < 0.05). Journal of Allergy and Clinical Immunology 1997 100, 216-221DOI: (10.1016/S0091-6749(97)70227-6) Copyright © 1997 Mosby, Inc. Terms and Conditions