Osmotic Shock and the Strength of Viral Capsids

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Osmotic Shock and the Strength of Viral Capsids Amado Cordova, Markus Deserno, William M. Gelbart, Avinoam Ben-Shaul  Biophysical Journal  Volume 85, Issue 1, Pages 70-74 (July 2003) DOI: 10.1016/S0006-3495(03)74455-5 Copyright © 2003 The Biophysical Society Terms and Conditions

Figure 1 Osmotic equilibrium as a function of the presence and configuration of confined polyelectrolyte. (a) Inside and outside salt concentrations are the same when the permeable capsid is empty. (b) Confined fixed charge leads to higher counterion density inside, due to Donnan equilibrium effects. (c) These effects are amplified by further confinement of a stiff chain, by avoidance of strong bending. Biophysical Journal 2003 85, 70-74DOI: (10.1016/S0006-3495(03)74455-5) Copyright © 2003 The Biophysical Society Terms and Conditions

Figure 2 Cell model depiction of fixed and mobile ion densities, inside and outside the hexagonally packed capsid (see text). Biophysical Journal 2003 85, 70-74DOI: (10.1016/S0006-3495(03)74455-5) Copyright © 2003 The Biophysical Society Terms and Conditions

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