The use of high-dose cyclophosphamide, carmustine, and thiotepa plus autologous hematopoietic stem cell transplantation as consolidation therapy for high-risk.

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Presentation transcript:

The use of high-dose cyclophosphamide, carmustine, and thiotepa plus autologous hematopoietic stem cell transplantation as consolidation therapy for high-risk primary breast cancer after primary surgery or neoadjuvant chemotherapy  Yee Chung Cheng, Gabriela Rondón, Ying Yang, Terry L. Smith, James L. Gajewski, Michele L. Donato, Elizabeth J. Shpall, Roy Jones, Gabriel N. Hortobagyi, Richard E. Champlin, Naoto T. Ueno  Biology of Blood and Marrow Transplantation  Volume 10, Issue 11, Pages 794-804 (November 2004) DOI: 10.1016/j.bbmt.2004.07.009 Copyright © 2004 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Kaplan-Meier overall relapse-free survival curve (all patients). Biology of Blood and Marrow Transplantation 2004 10, 794-804DOI: (10.1016/j.bbmt.2004.07.009) Copyright © 2004 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Kaplan-Meier overall survival curve (all patients). Biology of Blood and Marrow Transplantation 2004 10, 794-804DOI: (10.1016/j.bbmt.2004.07.009) Copyright © 2004 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Kaplan-Meier relapse-free survival curves by preoperative neoadjuvant chemotherapy. Biology of Blood and Marrow Transplantation 2004 10, 794-804DOI: (10.1016/j.bbmt.2004.07.009) Copyright © 2004 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 Kaplan-Meier overall survival curves by preoperative neoadjuvant chemotherapy. Biology of Blood and Marrow Transplantation 2004 10, 794-804DOI: (10.1016/j.bbmt.2004.07.009) Copyright © 2004 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 5 Kaplan-Meier relapse-free survival curves by disease stage at diagnosis. Biology of Blood and Marrow Transplantation 2004 10, 794-804DOI: (10.1016/j.bbmt.2004.07.009) Copyright © 2004 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 6 Kaplan-Meier overall survival curves by disease stage of diagnosis. Biology of Blood and Marrow Transplantation 2004 10, 794-804DOI: (10.1016/j.bbmt.2004.07.009) Copyright © 2004 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 7 Kaplan-Meier relapse-free survival curves by node ratio (number of metastatic axillary nodes divided by the number of nodes removed). Biology of Blood and Marrow Transplantation 2004 10, 794-804DOI: (10.1016/j.bbmt.2004.07.009) Copyright © 2004 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 8 Kaplan-Meier overall survival curves by node ratio (number of metastatic axillary nodes divided by the number of nodes removed). Biology of Blood and Marrow Transplantation 2004 10, 794-804DOI: (10.1016/j.bbmt.2004.07.009) Copyright © 2004 American Society for Blood and Marrow Transplantation Terms and Conditions