Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome After Pneumonectomy Jeremie Reeb, MD, MS, Anne Olland, MD, PhD, Julien Pottecher,

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Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome After Pneumonectomy Jeremie Reeb, MD, MS, Anne Olland, MD, PhD, Julien Pottecher, MD, PhD, Xavier Delabranche, MD, PhD, Mickael Schaeffer, MS, Stephane Renaud, MD, PhD, Nicola Santelmo, MD, Romain Kessler, MD, PhD, Gilbert Massard, MD, PhD, Pierre-Emmanuel Falcoz, MD, PhD The Annals of Thoracic Surgery Volume 103, Issue 3, Pages 881-889 (March 2017) DOI: 10.1016/j.athoracsur.2016.11.038 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Treatment protocol for postpneumonectomy acute respiratory distress syndrome (ppARDS). (PEEP = positive end-expiratory pressure; VV ECMO = venovenous extracorporeal membrane oxygenation.) The Annals of Thoracic Surgery 2017 103, 881-889DOI: (10.1016/j.athoracsur.2016.11.038) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Intensive care unit outcomes. (ECMO = extracorporeal membrane oxygenation.) The Annals of Thoracic Surgery 2017 103, 881-889DOI: (10.1016/j.athoracsur.2016.11.038) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Dynamics of gas exchange: (A) ratio of the partial pressure of oxygen in the radial arterial blood to the fraction of inspired oxygen (Pao2/Fio2) and (B) partial pressure of carbon dioxide in the radial arterial blood (Paco2). Data are illustrated as median and maximal value. (ANOVA = analysis of variance; ECMO = extracorporeal membrane oxygenation; ICU = intensive care unit.) The Annals of Thoracic Surgery 2017 103, 881-889DOI: (10.1016/j.athoracsur.2016.11.038) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Protective ventilation of postpneumonectomy acute respiratory distress syndrome patients supported with venovenous extracorporeal membrane oxygenation (ECMO). Comparison between pre-ECMO and ECMO (A) fraction of inspired oxygen (Fio2), (B) tidal volume (TV), (C) positive end-expiratory pressure (PEEP), and (D) measured plateau pressures. Data are illustrated as median and maximal value. #No statistical analysis was performed to compare pre-ECMO Fio2 vs ECMO Fio2. Indeed, pre-ECMO Fio2 had no variance: pre-ECMO Fio2 was 100% for every patient of the cohort. The Annals of Thoracic Surgery 2017 103, 881-889DOI: (10.1016/j.athoracsur.2016.11.038) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions