Monitoring and Prevention of Relapse after Allogeneic Hematopoietic Cell Transplantation for Myeloid Malignancies Ulrike Bacher, Julie-An Talano, Michael.

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Monitoring and Prevention of Relapse after Allogeneic Hematopoietic Cell Transplantation for Myeloid Malignancies Ulrike Bacher, Julie-An Talano, Michael R. Bishop Biology of Blood and Marrow Transplantation Volume 18, Issue 1, Pages S62-S73 (January 2012) DOI: 10.1016/j.bbmt.2011.10.028 Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 (A) Diagnostic strategies for MRD assessment in the transplantation setting in patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). I-FISH, interphase fluorescence in situ hybridization; RT-PCR, reverse transcription PCR; RQ-PCR, quantitative real-time PCR; mol., molecular; num., numerical; struct., structural. (B) Diagnostic strategies for MRD assessment in the transplantation setting in patients with chronic myeloid leukemia (CML). CHR, complete hematologic remission; TC, thrombocytes; GP, granulopoiesis; +Phi, additional Philadelphia chromosome; i(17q), isochromosome of 17q; CCgR, complete cytogenetic response; PCgR, partial; mCgR, minor; minCgR, minimal; noCgR, no cytogenetic response; MMR, major molecular response; CMR, complete molecular response; KD, kinase domain. Biology of Blood and Marrow Transplantation 2012 18, S62-S73DOI: (10.1016/j.bbmt.2011.10.028) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 (A) Diagnostic strategies for MRD assessment in the transplantation setting in patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). I-FISH, interphase fluorescence in situ hybridization; RT-PCR, reverse transcription PCR; RQ-PCR, quantitative real-time PCR; mol., molecular; num., numerical; struct., structural. (B) Diagnostic strategies for MRD assessment in the transplantation setting in patients with chronic myeloid leukemia (CML). CHR, complete hematologic remission; TC, thrombocytes; GP, granulopoiesis; +Phi, additional Philadelphia chromosome; i(17q), isochromosome of 17q; CCgR, complete cytogenetic response; PCgR, partial; mCgR, minor; minCgR, minimal; noCgR, no cytogenetic response; MMR, major molecular response; CMR, complete molecular response; KD, kinase domain. Biology of Blood and Marrow Transplantation 2012 18, S62-S73DOI: (10.1016/j.bbmt.2011.10.028) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions