The adverse prognostic effect of tumor budding on the evolution of cutaneous head and neck squamous cell carcinoma Miriam Gonzalez-Guerrero, MD, Pablo.

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Presentation transcript:

The adverse prognostic effect of tumor budding on the evolution of cutaneous head and neck squamous cell carcinoma Miriam Gonzalez-Guerrero, MD, Pablo Martínez-Camblor, MD, PhD, Blanca Vivanco, MD, PhD, Ivan Fernández-Vega, MD, PhD, Pablo Munguía-Calzada, MD, Maria Paz Gonzalez-Gutierrez, MD, Juan Pablo Rodrigo, MD, PhD, Cristina Galache, MD, PhD, Jorge Santos- Juanes, MD, PhD Journal of the American Academy of Dermatology Volume 76, Issue 6, Pages 1139-1145 (June 2017) DOI: 10.1016/j.jaad.2017.01.015 Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 A, Tumor budding at the invasive front in cutaneous squamous cell carcinoma. B, Tumor budding with hyperchromatic nuclei. Arrowheads indicate tumor buds. (Hematoxylin–eosin stain; original magnifications: A, ×20; B, ×40.) Journal of the American Academy of Dermatology 2017 76, 1139-1145DOI: (10.1016/j.jaad.2017.01.015) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 A, Kaplan–Meier estimates of nodal metastasis-free survival after resection of the primary cutaneous squamous cell carcinoma (cSCC). B, Kaplan–Meier estimates of overall survival after resection of the primary cSCC. C, Kaplan–Meier estimates of nodal metastasis-free survival after resection of the cSCC on the low and high tumor budding groups. D, Kaplan–Meier curve for survival after resection of the primary cSCC on the low and high tumor budding groups. Journal of the American Academy of Dermatology 2017 76, 1139-1145DOI: (10.1016/j.jaad.2017.01.015) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions