Eye color and the prediction of complex phenotypes from genotypes

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Eye color and the prediction of complex phenotypes from genotypes Fan Liu, Kate van Duijn, Johannes R. Vingerling, Albert Hofman, André G. Uitterlinden, A. Cecile J.W. Janssens, Manfred Kayser  Current Biology  Volume 19, Issue 5, Pages R192-R193 (March 2009) DOI: 10.1016/j.cub.2009.01.027 Copyright © 2009 Elsevier Ltd Terms and Conditions

Figure 1 Contribution of 24 SNPs to the prediction accuracy of human eye (iris) color in Dutch Europeans of the Rotterdam Study. Prediction performance measured by AUC for the model based on multinomial logistic regression (Y-axis) was plotted against the number of SNPs included in the model (X-axis). For each step, the lowest contributor in the model-building set (n = 3804) was excluded from the model; the model was rebuilt and used to predict eye color in the model-verification set (n = 2364). Current Biology 2009 19, R192-R193DOI: (10.1016/j.cub.2009.01.027) Copyright © 2009 Elsevier Ltd Terms and Conditions