Focus on hereditary endocrine neoplasia

Slides:



Advertisements
Similar presentations
Lessons from Hereditary Colorectal Cancer
Advertisements

Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr
Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher.
Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.
ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics Carlos L. Arteaga, Jeffrey A. Engelman Cancer Cell Volume.
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia Tim C.P. Somervaille, Michael L. Cleary Cancer Cell.
Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity Cai-Hong.
Modeling Inducible Human Tissue Neoplasia Identifies an Extracellular Matrix Interaction Network Involved in Cancer Progression Jason A. Reuter, Susana.
Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung Zvi Granot, Erik Henke, Elizabeth A. Comen, Tari A. King, Larry Norton, Robert Benezra.
Genetic testing for high-risk colon cancer patients1 William M. Grady Gastroenterology Volume 124, Issue 6, Pages (May 2003) DOI: /S (03)
Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm Thierry Soussi, Klas G. Wiman Cancer Cell Volume 12, Issue 4, Pages (October.
A Conditional Mouse Model for Malignant Mesothelioma Johan Jongsma, Erwin van Montfort, Marc Vooijs, John Zevenhoven, Paul Krimpenfort, Martin van der.
A Conditional Mouse Model of Synovial Sarcoma: Insights into a Myogenic Origin Malay Haldar, Jeffrey D. Hancock, Cheryl M. Coffin, Stephen L. Lessnick,
Tema: Etički problem: slučajno otkrivene patološke mutacije
Targeting HIF2α in Clear-Cell Renal Cell Carcinoma
Fig. 1. Serial changes of the Von Hippel Lindau (VHL) disease patient
Focus on lymphangiogenesis in tumor metastasis
Focus on endometrial and cervical cancer
Metastasis gets site specific
Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer
Management of advanced renal cancer
A Mitochondrial Power Play in Lymphoma
Three Down and One To Go: Modeling Medulloblastoma Subgroups
Multiple Effects of Angiopoietin-2 Blockade on Tumors
Killing Tumors by Keeping Ras and PI3′ Kinase Apart
Cell signaling and cancer
The linchpin? Pin1 meets p73
Volume 2, Issue 3, Pages (September 2002)
DAISY: Picking Synthetic Lethals from Cancer Genomes
Volume 26, Issue 1, Pages 1-2 (July 2014)
ABT-199: Taking Dead Aim at BCL-2
Fungating malignant phyllodes tumor
Pancreatic Cancer—Could It Be that Simple
A Radical Role for p38 MAPK in Tumor Initiation
Volume 4, Issue 1, Pages 4-6 (July 2003)
Volume 6, Issue 3, Pages (September 2004)
The p27Kip1 tumor suppressor gene: Still a suspect or proven guilty?
Targeting HIF2α in Clear-Cell Renal Cell Carcinoma
Focus on lymphangiogenesis in tumor metastasis
Microsatellite Instability in Benign Skin Lesions in Hereditary Non-Polyposis Colorectal Cancer Syndrome  Victoria J. Swale, Anthony G. Quinn, Veronique.
Richard G. Carroll, Seamus J. Martin  Cancer Cell 
Importance of Surveillance for Multiple Endocrine Neoplasia-1 and Surgery in Patients With Sporadic Zollinger–Ellison Syndrome  Maneesh H. Singh, Douglas.
Considering the critical interface between tumor cells and stromal cells in the search for targets for anticancer therapy  Laurence Blavier, Yves A. DeClerck 
Frances Balkwill, Kellie A. Charles, Alberto Mantovani  Cancer Cell 
An Integrin-Linked Machinery of Cytoskeletal Regulation that Enables Experimental Tumor Initiation and Metastatic Colonization  Tsukasa Shibue, Mary W.
Antigen-Presenting Cells: Professionals and amateurs
Breaking News on Fragile Sites in Cancer
Volume 64, Issue 5, Pages (November 2003)
847. Eradication of Therapy-Resistant Human Prostate Tumors Using an Ultrasound Guided Site-Specific Cancer Terminator Virus Delivery Approach    Molecular.
Erik C. von Rosenvinge, MD, Stephen A. Wank, MD, Ramona M. Lim, MD 
Bmi1 and Cell of Origin Determinants of Brain Tumor Phenotype
Multiple Effects of Angiopoietin-2 Blockade on Tumors
Volume 17, Issue 2, Pages (February 1950)
Volume 14, Issue 4, Pages (October 2008)
Volume 16, Issue 3, Pages (September 2009)
The Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand and Lung Cancer: Still Following the Right TRAIL?  Emmet E. McGrath, MB, PhD  Journal of Thoracic.
International Thymic Malignancies Interest Group: A Way Forward
A common pathway for genetic events leading to pheochromocytoma
To Infinium, and Beyond! Cancer Cell
Volume 10, Issue 3, Pages (September 2006)
Co-opted integrin signaling in ErbB2-induced mammary tumor progression
Volume 163, Issue 2, (October 2015)
There's a Time and a Place for MYCN
Volume 17, Issue 2, Pages (February 2010)
Ibrutinib Treatment of CLL: The Cancer Fights Back
Pharmacological Rescue of p53 in Cancer Therapy: Widening the Sensitive Tumor Spectrum by Targeting MDMX  Jean-Christophe Marine  Cancer Cell  Volume.
Volume 12, Issue 6, Pages (December 2007)
The Ups and Downs of Src Regulation: Tumor Suppression by Cbp
A “Big Data” View of the Tumor “Immunome”
Presentation transcript:

Focus on hereditary endocrine neoplasia Allen M. Spiegel  Cancer Cell  Volume 6, Issue 4, Pages 327-332 (October 2004) DOI: 10.1016/j.ccr.2004.09.023

Figure 1 Major sites developing benign and/or malignant tumors in endocrine neoplasia syndromes Multiple endocrine neoplasia types 1 and 2 (MEN1 and MEN2, respectively), McCune-Albright syndrome (MAS), Carney complex (CNC), hyperparathyroidism-jaw tumor syndrome (HPT-JT), hereditary paranganglioma syndrome (PGL), and von Hippel-Lindau disease (VHL). Cancer Cell 2004 6, 327-332DOI: (10.1016/j.ccr.2004.09.023)