Definitions: Seizure, Epilepsy, Epilepsy Syndrome

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Presentation transcript:

Definitions: Seizure, Epilepsy, Epilepsy Syndrome

Goals of Medical Therapy

Individualizing AED Selection

Comorbidities

AED Mechanisms of Action

Effectiveness of AED Combination Therapy Based on Mechanism of Action

Effectiveness of AED Combination Therapy Based on Mechanism of Action (cont)

Newest AEDs for Partial-Onset Seizures

Clobazam: Indication

Clobazam: MOA and Pharmacokinetics

Clobazam: Clinical Efficacy

Clobazam: Adverse Effects

Clobazam: Drug Interactions

Clobazam: Summary/Dosing

Eslicarbazepine Acetate: Indication/ MOA

Eslicarbazepine: Pharmacokinetics

Eslicarbazepine: Clinical Efficacy

Eslicarbazepine: Efficacy (cont)

Eslicarbazepine: Adverse Effects

Eslicarbazepine: Drug Interactions/Dosing

Ezogabine: Indication/MOA

Ezogabine: Pharmacokinetics

Ezogabine: Clinical Efficacy

Ezogabine: Adverse Effects

Ezogabine: Adverse Effects (cont)

Ezogabine: Dosing

Perampanel: Indication/MOA

Perampanel: Pharmacokinetics

Perampanel: Clinical Efficacy

Perampanel: Pooled Analysis of 3 Phase 3 Studies

Perampanel: Adverse Effects

Perampanel: Drug Interactions

Perampanel: Dosing

Perampanel: Dosing (cont)

Abbreviations

Abbreviations (cont)

References

References (cont)

References (cont)

References (cont)