Key clinical efficacy outcomes for (A) hemoglobin A1c (HbA1c), (B) weight change. Key clinical efficacy outcomes for (A) hemoglobin A1c (HbA1c), (B) weight change. Data points are mean change from baseline absolute HbA1c (A) or mean change from baseline absolute body weight (B) and error bars represent SEM for n=15 patients. Data below the charts are absolute mean and median HbA1c (A) or mean and median % body weight reduction (*p<0.05) compared with baseline values. Martin Fried et al. BMJ Open Diab Res Care 2017;5:e000431 ©2017 by American Diabetes Association