Toward Universal Flavivirus Identification by Mass Cataloging

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Presentation transcript:

Toward Universal Flavivirus Identification by Mass Cataloging George W. Jackson, Roger J. McNichols, George E. Fox, Richard C. Willson The Journal of Molecular Diagnostics Volume 10, Issue 2, Pages 135-141 (March 2008) DOI: 10.2353/jmoldx.2008.070130 Copyright © 2008 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 1 Cluster analysis based on mass spectral patterns of flaviviruses amplified by universal PCR of the NS5 coding region and fragmented by RNase T1. The Journal of Molecular Diagnostics 2008 10, 135-141DOI: (10.2353/jmoldx.2008.070130) Copyright © 2008 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 2 Dengue serotype clustering based on mass fragments between primers described by Drosten et al.15 The Journal of Molecular Diagnostics 2008 10, 135-141DOI: (10.2353/jmoldx.2008.070130) Copyright © 2008 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 3 Representative mass spectrum for dengue virus type-1 corresponding to the fragments derived using universal flavivirus primers analyzed in the cluster analysis of Figure 1. The Journal of Molecular Diagnostics 2008 10, 135-141DOI: (10.2353/jmoldx.2008.070130) Copyright © 2008 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions