DNA Replication.

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Presentation transcript:

DNA Replication

DNA Replication Replication = DNA copies itself exactly (Occurs within the nucleus) Any mistake in copying = mutation DNA mutation = chromosomal mutation

A. Basic Facts of DNA Replication 1. Complementary base pairing makes replication possible C - G A - T

A. Basic Facts of DNA Replication 2. One side of DNA molecule is a template for making the other side (strand) ?’s 1-3

B. Process of DNA Replication Uncoil & unzip DNA molecule Enzyme (-ase) breaks weak Hydrogen Bond between bases

B. Process of DNA Replication 2. Enzyme brings in complementary N-bases DNA Replicase

B. Process of DNA Replication 3. Insert N-bases DNA Replication Tutorial (Go here for on-your-own learning/review) trc.ucdavis.edu/.../week5/06dnareplication.html

Replication Moovie C - G A - T

C. Semi-conservative replication Each new DNA molecule contains one old strand & one new strand ?’s 4-6

DNA vs. RNA DNA RNA Sugar = deoxyribose Sugar = ribose Double-stranded molecule Single-stranded molecule Thymine bonds with adenine Uracil instead of thymine

DNA vs. RNA DNA RNA Nuclear DNA Mitochondrial DNA Chloroplast DNA mRNA = messenger tRNA = transfer rRNA = ribosomal Nuclear DNA never leaves the nucleus Assembled in nucleus, moves to cytoplasm (leaves the nucleus)

DNA vs. RNA