War on Viruses: LC3 Recruits GTPases

Slides:



Advertisements
Similar presentations
Waging War on Cancer with the Sword of Immunity Cell Volume 158, Issue 2, (July 2014) DOI: /j.cell Copyright © 2014 Terms and Conditions.
Advertisements

Human Gut Microbes Use Multiple Transporters to Distinguish Vitamin B12 Analogs and Compete in the Gut Patrick H. Degnan, Natasha A. Barry, Kenny C. Mok,
Nucleocapsid Phosphorylation and RNA Helicase DDX1 Recruitment Enables Coronavirus Transition from Discontinuous to Continuous Transcription Chia-Hsin.
Genes Induced Late in Infection Increase Fitness of Vibrio cholerae after Release into the Environment Stefan Schild, Rita Tamayo, Eric J. Nelson, Firdausi.
The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin- Dependent Autophagy of Intracellular Salmonella Typhimurium Alan Huett, Robert.
A View to a Kill: The Bacterial Type VI Secretion System Brian T. Ho, Tao G. Dong, John J. Mekalanos Cell Host & Microbe Volume 15, Issue 1, Pages 9-21.
Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming Smita Srivastava, Joel D. Ernst Cell Host & Microbe Volume 15, Issue 6,
Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7 Hyun.
RAS and ROS—A Story of Pseudomonas Survival
Trained Immunity: An Ancient Way of Remembering
Influenza A Virus Lures Autophagic Protein LC3 to Budding Sites
The Avian Influenza Virus Polymerase Brings ANP32A Home to Roost
AMPK-Dependent Phosphorylation of ULK1 Induces Autophagy
Balance of Power in Host-Virus Arms Races
Jenner's Irony: Cowpox Taps into T Cell Evasion
Mammalian PGRPs Also Mind the Fort
NMD: Nonsense-Mediated Defense
Bacterial Reductionism: Host Thiols Enhance Virulence
Shigella Stays on the Move
Three Rules for HIV Latency: Location, Location, and Location
Measles Virus Takes a Two-Pronged Attack on PP1
Warfare between Host Immunity and Bacterial Weapons
Arturo Casadevall, Liise-anne Pirofski  Cell Host & Microbe 
Endosomes as Platforms for NOD-like Receptor Signaling
Christopher D. Dupont, Christopher A. Hunter  Immunity 
Shigella Targets T Cells
Octavio Ramilo, Asunción Mejías  Cell Host & Microbe 
Dynamins Are Forever: MxB Inhibits HIV-1
Volume 22, Issue 5, Pages (November 2017)
Autophagy, Apoptosis, and the Influenza Virus M2 Protein
A Microbiome Foundation for the Study of Crohn’s Disease
Type VI Secretion: Not Just for Pathogenesis Anymore
Volume 22, Issue 3, Pages (September 2017)
A RIPtide Protects Neurons from Infection
A Serpin Takes a Bite out of the Flu
Gabriel Mitchell, Ralph R. Isberg  Cell Host & Microbe 
The Avian Influenza Virus Polymerase Brings ANP32A Home to Roost
Restriction of Zika Virus by Host Innate Immunity
Exploring New Horizons in Microbiome Research
Mycobacterial Lipid Logic
Breaking the Barrier: Host Cell Invasion by Lujo Virus
Volume 22, Issue 1, Pages e7 (July 2017)
Nucleophagy: A New Look at Past Observations
SARS-CoV and IFN: Too Little, Too Late
HATs On for Drug Resistance
Tumor Metabolism: MAGE-A Proteins Help TRIM Turn Over AMPK
Volume 2, Issue 4, Pages (October 2007)
Recognizing Macrophage Activation and Host Defense
RNA Virus Harnesses MicroRNAs to Seize Host Translation Control
Caging Targets for Destruction
First Impressions in a Glowing Host-Microbe Partnership
Gut Microbes Take Their Vitamins
Linking Inflammasome Activation and Phagosome Maturation
A Microbiome Foundation for the Study of Crohn’s Disease
Inside Job: Viruses Transfer cGAMP between Cells
A Vitamin for Autophagy
The Yeast Saccharomyces cerevisiae: A Versatile Model System for the Identification and Characterization of Bacterial Virulence Proteins  Keri A. Siggers,
For HIV, It's Never Too Late to Grow Up
Wilbert Bitter, Coen Kuijl  Cell Host & Microbe 
Viral Suppressors of RNA-Based Viral Immunity: Host Targets
Getting a gRIP on Flu by Casting the DAI
Jun-Young Seo, Rakina Yaneva, Peter Cresswell  Cell Host & Microbe 
Streptococcus pyogenes Escapes from Autophagy
Viperin Poisons Viral Replication
Apicomplexan AMA1 in Host Cell Invasion: A Model at the Junction?
Understanding How Hepatitis C Virus Builds Its Unctuous Home
A Host MicroRNA Brokers Truce with HSV-1
Jenner's Irony: Cowpox Taps into T Cell Evasion
Volume 63, Issue 6, Pages (September 2016)
Time Heals All Wounds … But Wounds Heal Faster with Lactobacillus
Presentation transcript:

War on Viruses: LC3 Recruits GTPases Teneema Kuriakose, Thirumala-Devi Kanneganti  Cell Host & Microbe  Volume 22, Issue 1, Pages 7-9 (July 2017) DOI: 10.1016/j.chom.2017.06.019 Copyright © 2017 Terms and Conditions

Figure 1 Coordinated Action of the LC3 Conjugation System of Autophagy and IFN-Inducible GTPases Inhibits Replication of MNV The replication complex of MNV is marked by the LC3 conjugation system and then targeted by IRG and GBP proteins upregulated in response to IFNγ. IFNγ also promotes localization of LC3 to RC. Localization of IRG and GBP proteins to RC membrane disrupts these structures and inhibits MNV replication. Cell Host & Microbe 2017 22, 7-9DOI: (10.1016/j.chom.2017.06.019) Copyright © 2017 Terms and Conditions

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.