Ibrutinib-associated pityriasis rosea–like rash

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Ibrutinib-associated pityriasis rosea–like rash Carole Bitar, MD, Azeen Sadeghian, MD, Lacey Sullivan, MD, Andrea Murina, MD JAAD Case Reports Volume 4, Issue 1, Pages 55-57 (January 2018) DOI: 10.1016/j.jdcr.2017.06.035 Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Clinical images of the rash over the right flank and right axilla. A, A 3-cm violaceous plaque with an inward-facing central scale on the right flank. B, Multiple grouped violaceous scaly papules each measuring 0.5 to 1 cm under the right axilla. JAAD Case Reports 2018 4, 55-57DOI: (10.1016/j.jdcr.2017.06.035) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Histopathologic images of punch biopsy specimens obtained from the right flank. A, Superficial perivascular infiltrate with spongiosis. B, Perivascular cell infiltrates consisting of lymphocytes and eosinophils, suggestive of drug eruption. (Hematoxylin–eosin stain; original magnification: A, ×4; B, ×10.) JAAD Case Reports 2018 4, 55-57DOI: (10.1016/j.jdcr.2017.06.035) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions