Kay E Gurley, Christopher J Kemp Current Biology

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Synthetic lethality between mutation in Atm and DNA-PKcs during murine embryogenesis Kay E Gurley, Christopher J Kemp Current Biology Volume 11, Issue 3, Pages 191-194 (February 2001) DOI: 10.1016/S0960-9822(01)00048-3

Figure 1 Simultaneous loss of DNA-PKcs and Atm results in early embryonic lethality. Shown are embryos within yolk sacs isolated at E8.5. On the left is a Prkdcscid/scid Atm+/+ conceptus showing a normal appearing embryo (arrows) within the yolk sac (A, anterior; P, posterior). The three much smaller concepti on the right are Prkdcscid/scid Atm−/− and show arrested development Current Biology 2001 11, 191-194DOI: (10.1016/S0960-9822(01)00048-3)