Immune System.

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Presentation transcript:

Immune System

Why do we need the immune system? *pathogens* 3 Lines of Defense

First and Second Line of Defense (Innate) (non-specific) (genetic) Physical Barriers 2. Chemical Barriers See Table 21.1 in text!

3. Cellular Defenses – Defensive Cells Granulocytes Include: Basophils Mast cells Eosinophils Neutrophils (polymorphonuclear leukocytes) Dendritic cells

Agranulocytes Monocytes Lymphocytes Natural Killer Cells: targets cells with abnormal or unusual plasma membrane membrane

4. Inflammation Triggers – abrasions, pathogens, chemical irritations, distortion or disturbances of cells, and extreme temps. Functions – Characterized by cardinal signs: calor rubor tumor dolor Histamine, bradykinins, prostaglandins,

5. Fever (aka pyrexia) Febrile Function pyrogens

6. Molecular Defenses (both innate and adaptive!) Interferon Complement Iron-binding proteins Defensins

Questions 21.14 Name the physical and chemical factors that provide protection from disease in the skin and mucus membranes. 21.15 Which internal defenses provide protection against microbes that penetrate the skin and mucous membranes? 21.16 What is the name for the antimicrobial proteins that prevent viral replication? 21.18 Describe the phases of phagocytosis. 21.19 How are microbes killed following their ingestion by a phagocyte?

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