Imidazole alkaloids.

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Imidazole alkaloids

Imidazole Alkaloid Biosynthetic origin: Examples: Pilocarpine Botanical sours are Pilocarpus jaborandi Rutaceae. Pharmacological effect: Parasympathomimetic Uses: in Glaucoma (wide and narrow angle Glaucoma) and myosis of the eye. Keep away from light. Side effect: bronco contraction, brady cardiac, not first choice for glaucoma because headache and increase in lacrimation.

Imidazole alkaloid

Indole alkaloids

( Periwincle, Rauwolfia, Nux-vomica, physostigma, Ergot) Indole alkaloid: ( Periwincle, Rauwolfia, Nux-vomica, physostigma, Ergot) Biosynthetic origin: Ergot: fungus grow on Rye and Cereals. - Botanical sours are fungus of Claceveceps purpurea Clavecpetaceae Sant antony fire→ inflammation → redness then vasoconstriction (cyanosis) → loss limbs and extremities the death. Convulsion and delirium.