Volume 146, Issue 4, Pages (April 2014)

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Volume 146, Issue 4, Pages 906-909 (April 2014) Transplantation of Mucosa From Stomach to Esophagus to Prevent Stricture After Circumferential Endoscopic Submucosal Dissection of Early Squamous Cell  Juergen Hochberger, Peter Koehler, Edris Wedi, Sylvia Gluer, Richard I. Rothstein, Heiner Niemann, Andres Hilfiker, Susana Gonzalez, Elena Kruse  Gastroenterology  Volume 146, Issue 4, Pages 906-909 (April 2014) DOI: 10.1053/j.gastro.2014.01.063 Copyright © 2014 AGA Institute Terms and Conditions

Figure 1 A, i–vi, Mucosal squamous cell cancer in the cervical esophagus with circumferential spread and extension through the sphincter area to the hypopharynx (Ai, ii). Tubular craniocaudal endoscopic en bloc resection of the infiltrated mucosa over 11 cm using the submucosa dissection technique (ESD; Aiii, iv, v) and retrieval of the contracted specimen (Avi). (Bi-vi) Second 9 × 4- to 6-cm, widespread ESD resection in the gastric antrum to provide a mucosal specimen, which is cut into 3 slices using a surgical pair of scissors (Bi, ii, iii). The gastric transplant is then attached to the denuded muscular esophageal wall by means of endoscopic clips and a noncovered, self-expanding metal stent to allow luminal nutrition of the mucosal specimen (Biv, v, vi). The cervical sphincter area had to be spared to avoid severe pain and potential larynx compression. Gastroenterology 2014 146, 906-909DOI: (10.1053/j.gastro.2014.01.063) Copyright © 2014 AGA Institute Terms and Conditions

Figure 2 (A–C) Stepwise, circumferential spread of the transplanted gastric mucosa in the cervical esophagus with effective stricture prevention (A, C). (B) Biopsy-proven Hp-negative antral mucosa at the site of the transplant. Gastroenterology 2014 146, 906-909DOI: (10.1053/j.gastro.2014.01.063) Copyright © 2014 AGA Institute Terms and Conditions