Intro to DNA Replication
A QUICK REFRESHER Where is DNA found? nucleus Where else? mitochondria, chloroplast (the endosymbiont theory) What form does DNA take in the nucleus? chromosome How do the 150 million base pairs that make up the human genome fit into the nucleus? wrapped around histones coiled and supercoiled chromatin condenses into chromosomes
What is a karyotype? A picture of all the chromosomes found in a cell How many chromsomes are found in a human somatic cell? 23 pairs (46 total) How many chromosomes are found in human gametes? 23 Is this person male or female? male
All cells can give rise to a new generation of cells via the cell cycle S phase of interphase DNA replicates Mitosis Replicated DNA splits between two nuclei Cytokinesis Cytoplasm splits between two daughter cells Each daughter cell has an exact copy of the parent cell’s DNA
Meselson and Stahl
DNA Replication - The Process