Amino Acid Activation And Translation.

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Amino Acid Activation And Translation

Transcription - 1st step in protein synthesis Transcription - 1st step in protein synthesis. Formation of mRNA in the nucleus by complimentary base pairing with DNA. mRNA then leaves the nucleus and travels to the Ribosome. Ribosomes Read the mRNA in code. Codon - a sequence of three bases in mRNA. There are 64 different codons and 20 different amino acids. Several amino acids have several different codons that code for them. One Codon is the “Start Codon” AUG and also codes for methionine. Three codons are “Stop Codons” UAA, UAG, UGA

U A U G G C A U U A G C U A A G C U A G A T A C C G T A A T C G A T T C G A T C Original DNA Strand U A U G G C A U U A G C U A A G C U A G mRNA Strand

U A U G G C A U U A G C U A A G C U A G mRNA

Amino Acid Activation - 2nd step in protein synthesis. tRNA - Transfer RNA, carries specific amino acids to the Ribosomes. (Enzymes insure specific amino acids attach to specific tRNA) Anticodon - site on tRNA that is complimentary to a codon on mRNA

Translation - 3rd and final stage in protein synthesis. Ribosome reads mRNA, one codon at a time. (beginning at the start codon AUG) The complimentary tRNA anti-codon attaches to the codon. Amino acids on the tRNA are linked in sequence by peptide bonds. Ribosome releases protein when stop codon is reached. Each section of DNA codes for a specific protein. This is called One Gene - One Polypeptide

Assignment : Using your mRNA code, identify the sequence of condons and anti-codons the ribosome would read during translation. A U G A U G

A U G A U G

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