Lorelei L. Vicente, M.D. Brian S. Boxer Wachler, M.D.

Slides:

Advertisements

Similar presentations

Topography-Guided Photorefractive Keratectomy (TG-PRK) and Simultaneous collagen cross-linking (CXL) in Post-LASIK Ectasia Using 2 High-Resolution Excimer.

Advertisements

Dose-response for Mitomycin-C in prevention of haze in photorefractive keratectomy for high myopia: Six month preliminary results CDR Elizabeth M. Hofmeister,

Paradox of Corneal CXL and Infectious Keratitis: To Do or Not to Do? None of the authors have any financial disclosure to make Vishal Vohra,MS (Presenting.

George J. Pardos, M.D...1 George J. Pardos, M.D.. Ophthalmologist: Fellowship Trained in Cornea and External Disease.

Untraviolet Riboflavin Collagen Crosslinking in Keratoconus – Initial Results J Brady, W Power, W Lee The Authors have no financial interetsts in the subject.

USE OF HYALURONIDASE ENZYME IN TOPICAL ANAESTHESIA Gianluca Rubiolini M.D. ITALY.

Northern Colorado Eye Center Continuing Education Event Corneal Collagen Cross-linking September 20, 2014 S. Lance Forstot, MD, FACS Corneal Consultants.

Instructional course IC 1 Corneal cross linking therapy: Operative technique Auhor: Kristina Mikek, Slovenia Co. Authors : Carina Koppen, Belgium Zoltan.

Corneal melting after collagen cross-linking for keratoconus Journal of Medical Case Reports,2011 By Ibrahim almahuby Dr.Georgios Labiris.

Corneal collagen cross-linking (CXL) ALIREZA PEYMAN, MD ISFAHAN UNIVERSITY OF MEDICAL SCIENCES.

TELEMEDICINE IN THE MODERN EYE BANK Eric Abdullayev MD, MBA,CEBT International Sight Restoration Eye Bank (ISR), Tampa FL, USA Author Has No Financial.

Corneal Cross Linking By Chris Fauria. 2 Keratoconus Affects 1 in 1,000 people Symptoms: blurry vision, double vision, trouble seeing at night, headaches.

Brian S. Boxer Wachler, MD Ten Year Followup of First Reported Case of Intacs for Keratoconus in North America BEVERLY HILLS, CA.

Femtosecond laser for INTACS and Cross-linking: Combined Procedure Faik Orucov, Mahir Kendusim, Buket Ayoglu, Sinan Goker Istanbul Surgery Hospital, Istanbul/Turkey.

USE OF THE KONAN NONCON-ROBO SPECULAR MICROSCOPE IN CLINICAL RESEARCH

Clinical Specular Microscopy Corneal Endothelial Cell Morphology

Evaluation of Bactericidal and Fungicidal Activity of Riboflavin Plus UVA Irradiation for Corneal CXL Authors Ashok Sharma, Cornea Centre, Chandigarh,

UVA/riboflavin for infectious keratitis. Prospective randomized double blind trial. Early experience. Erik Letko, MD 1 ; Francis W. Price, MD 1 ; Carlindo.

Prof. A. John Kanellopoulos, MD 1 Long-term Safety and Efficacy of High-Fluence Collagen Crosslinking of the Vehicle Cornea in.

Elias F. Jarade, MD, FICS. Corneal and Refractive Surgery Service, The Dubai Mall Medical Center, Dubai- U.A.E. Tel: ; Mob

Collagen cross-linking (CXL) for keratoconus (KC) with simultaneous topographical-guided photorefractive keratectomy (TG-PRK) Simon Holland, MD, FRCSC,

Pachymetric changes during corneal collagen cross-linking and effect of hydroxipropylmethylcellulose on corneal thickness Faik Oruçoğlu (Orucov) Kudret.

Corneal CXL in Children With Progessive Keratoconus Author do not have any financial interest in the surgical procedure or the medicines used in this study.

Deep Anterior Lamellar Keratoplasty in Herpes Simplex Corneal Opacities V. Sarnicola Italy ASCRS-ASOA ANNUAL MEETING Boston April 9-14, 2010.

Effects of Intracameral Moxifloxacin, Levofloxacin, and Cefazolin on Corneal Endothelial Cells in Rabbits Su-Young Kim, Department of Ophthalmology and.

Relocating corneal endothelial area by non-contact specular microscopy Tomoyuki Kunishige, M.D., Hisaharu Suzuki, M.D., Hideaki Oharazawa, M.D., Toshihiko.

“Corneal CXL for the Treatment of Non- Responding Infectious Keratitis ” Cristian A. Cartes, MD ; Miguel Srur, MD; Leonidas Traipe, MD Fundación Oftalmológica.

Results of Collagen Crosslinking followed by posterior chamber toric implantable collamer lens implantation in patients with Keratoconus & High Myopia.

1 Non-contact Specular Microscopy for Evaluation of Corneal Endothelium in Early Fuchs’ Endothelial Corneal Dystrophy Jianyan Huang 1, MD, PhD; Tudor Tepelus.

Factors which Influence Accommodative Amplitude in Crystalens HD Patients Uday Devgan, MD, FACS Devgan Eye Surgery, Los Angeles, CA FINANCIAL DISCLOSURES:

Anesthetic Effect of Topical Agents in Cataract Surgery Ross B. L. MacIntyre, MD Paul S. Koch, MD Dr. Ross MacIntyre has no financial interests to disclose.

Thomas John, MD Clinical Associate Professor Loyola University at Chicago Maywood, Illinois Ritika Patel Chicago Medical School.

Three-Year Study Results of Trans-epithelial Corneal Collagen Crosslinking for Keratoconus Brian S. Boxer Wachler, M.D. Lorelei L. Vicente, M.D. BEVERLY.

Diminished Endothelial Cell Counts in Corneas with Krukenberg Spindles Authors: Tod M. Haller1, Chad B. Haller2, Melvin L. Haller1, Judah Beck3, Keith.

Prevention of epithelial in-growth following LASIK enhancement surgery Mark E Johnston MD FRCSC Omaha NE NO FINANCIAL INTERESTS.

First 25 Descemet Membrane Endothelial Keratoplasty (DMEK) Outcomes for an Experienced DSAEK Surgeon Authors: Victoria Epstein, MS.,DO, Josh Wallsh, MS-III,

Poster produced by Faculty & Curriculum Support (FACS), Georgetown University School of Medicine LASIK Combined with Corneal Cross-linking in Eyes with.

Liquifaction Method and Extent of Posterior Capsule Opacification: Two-Year Follow-up Marie Kalfertova, Mariya Burova, Pavel Rozsival, Nada Jiraskova Nada.

Corneal Endothelial Cell Changes After LASIK Using a Femtosecond Laser Minoru Tomita, MD, PhD, Masaru Aoyama, MD, Minoru Tomita, MD, PhD, Masaru Aoyama,

D.r Nishant Nawani, MS Dr. Surinder Singh Pandav, MD Dr. Amit Gupta, MD Dr. Sushmita Kaushik, MD Advanced Eye Centre PGIMER, Chandigarh The authors have.

CORNEAL ENDOTHELIAL PROFILE AFTER FERRARA RING IMPLANTATION Leonardo Torquetti, MD, PhD Paulo Ferrara, MD, PhD Paulo Ferrara Eye Clinic Belo Horizonte.

Demographic and visual outcomes on keratoconus patients with failed “epi- on”C3R cross-linking procedures Yaron S. Rabinowitz M.D. Oana Dumitrascu M.D.

FreeVis LASIK Zentrum Universitätsklinikum Mannheim

Evaluation of Topography-guided LASIK and Simultaneous Collagen Cross-linking in the Management of Post-LASIK Ectasia Diana Ng, MD1 Anastasios John Kanellopoulos,

Comparison of Endothelial Cell Loss After Phacoemulsification Performed by Third Year Residents and Anterior Segment Surgeons Alexandra Braunstein, MD.

Low intensity versus high intensity CXL

Prophylactic collagen cross-linking (pCXL) in high risk (HR) LASIK

Influence of UVA-Riboflavin corneal collagen cross-linking on biomechanical properties of keratoconic eyes David Zadok MD, Yakov Goldich MD, Yaniv Barkana.

DSAEK using corneas with previous LASIK

Crosslinking with Simultaneous Implantation of Intrastromal Corneal Ring Segments in Keratoconus: Safe and Efficacy Author: Luiz Antonio de Brito Martins.

Prospective Study Comparing Outcomes of Torsional versus Traditional Phacoemulsification Systems on Dense Cataracts Bonnie An Henderson MD, Kelly J Grimes.

Collagen cross-linking (CXL) for keratoconus (KC) with simultaneous topographical-guided photorefractive keratectomy (TG-PRK) Simon Holland, MD, FRCSC,

Diminished Endothelial Cell Counts in Corneas with Recurrent Erosions

post-lasik corneal ectasia

Effects of corneal collagen crosslinking on Ocular Response Analyzer waveform-derived variables in keratoconus and post-LASIK ectasia Spatial treatment.

No Financial Interest in Study Material

University of Ulsan College of Medicine

Corneal Effects of 1.5% Levofloxacin Ophthalmic Solution (IQUIX®) in Humans Mark B. Abelson, MD1,2 Gail Torkildsen, MD2; Aron Shapiro2; Ingrid Lapsa2.

Pachymetry Fluctuations During Corneal Crosslinking (CXL)

Faik Oruçoğlu (Orucov) Kudret Eye Hospital / Istanbul

DARIUSZ DOBROWOLSKI¹, EDWARD WYLĘGAŁA¹ ², DOROTA TARNAWSKA¹

Corneal Endothelial Damage Rate in Middle-Aged and Elderly Japanese.

The authors have no financial interest to disclosure

Yakov Goldich MD,Yaniv Barkana MD, Isaac Avni MD, David Zadok MD,

Brian S. Boxer Wachler, MD

Satisfaction Survey of Presbyopic LASIK Patients Up to 11 Years Postop

Novel Cornea OCT (cOCT) findings in early and long term follow up of collagen cross-linking (CXL) for keratoconus (KCN) ASCRS, Boston 2010 John Kanellopoulos,

Shorter Duration, Higher Ultraviolet A Irradiation (UVA) Fluence Collagen Cross-linking (CCL) for Keratoconus (KCN) Frank A. Killian, MD and A. John Kanellopoulos,

Majid Moshirfar, MD, FACS

Comparing Endothelial Cell Density after Sub-Bowman’s Keratomileusis and Photorefractive Keratectomy for the Treatment of Myopia Ryan T. Smith, MD Daniel.

Presentation transcript:

Lorelei L. Vicente, M.D. Brian S. Boxer Wachler, M.D. One Year Safety Analysis of Endothelial Cell Counts of Trans-Epithelial Corneal Crosslinking for Keratoconus Lorelei L. Vicente, M.D. Brian S. Boxer Wachler, M.D. BEVERLY HILLS , CA

Disclosure Financial declaration/conflict of interest: Dr. Boxer Wachler is consultant to Addition Technology and Staar Surgical. Dr. Vicente has no financial interest in the subject matter of this paper.

Purpose To assess change in endothelial cell count (ECC) of patients with keratoconus after trans-epithelial corneal collagen crosslinking with riboflavin-carboxymethylcellulose (RF-CMC).

Methods Trans-Epithelial Crosslinking using 66 eyes of 45 patients (39 +/- 14 y.o.) Trans-Epithelial Crosslinking using 0.1 % riboflavin with 0.5% carboxymethylcellulose (RF-CMC) and Tetracaine keratoconus – 56 eyes (86%) keratectasia – 10 eyes (14%) post LASIK - 8 eyes post RK - 2 eyes 26 eyes (39%) - Trans-Epithelial Crosslinking only 40 eyes (61%) - Intacs and Trans-Epithelial Crosslinking

Methods Specular microscopy IConan Noncon ROBO SP-9900 Dot method Konan Medical Inc., Hyogo, Japan Dot method 70 contiguous cells are marked to estimate endothelial cell density

Trans-Epithelial Crosslinking Pretreatment with Tetracaine and RF-CMC Instilled one drop after another every 5 minutes for 15 minutes Trans-Epithelial Crosslinking Protocol RF-CMC (q 3 min.) & Tetracaine (q 10 min.) for 30 mins. Applied via soppy, wet surgical sponges (Merocel eye spears, Medtronic, Jacksonville, FL) Ultraviolet-A light (3.0 mW/cm2 at 370 nm)

Results

Conclusion (RF-CMC) is Safe to the Endothelium Trans-Epithelial Crosslinking using 0.1% riboflavin w/ 0.5% CMC (RF-CMC) is Safe to the Endothelium