Ruben Hernaez, MD, MPH, PhD  Clinical Gastroenterology and Hepatology 

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High Negative Predictive Value, Low Prevalence, and Spectrum Effect: Caution in the Interpretation  Ruben Hernaez, MD, MPH, PhD  Clinical Gastroenterology and Hepatology  Volume 15, Issue 9, Pages 1355-1358 (September 2017) DOI: 10.1016/j.cgh.2017.05.002 Copyright © 2017 AGA Institute Terms and Conditions

Figure 1 Example of effect of population prevalence on the values of positive and negative predictive values, using a test with a sensitivity and specificity of 85%. Reprinted, with permission, from van Stralen et al.17 Clinical Gastroenterology and Hepatology 2017 15, 1355-1358DOI: (10.1016/j.cgh.2017.05.002) Copyright © 2017 AGA Institute Terms and Conditions