Response of plasma matrix metalloproteinases and tissue inhibitor of metalloproteinases to stent-graft surgery for descending thoracic aortic aneurysms 

Slides:



Advertisements
Similar presentations
Endovascular Repair of Thoracoabdominal Aortic Aneurysms with Fenestrated- Branched Stent-Grafts Edward G. Soltesz, MD, MPH, Roy K. Greenberg, MD Operative.
Advertisements

Of mice and men and surgical transcatheter aortic valve insertion
Lost in translation The Journal of Thoracic and Cardiovascular Surgery
Complicated acute type B aortic dissection involving the arch: Treatment by simultaneous hybrid approach under local anesthesia  Gabriele Iannelli, MD,
Endovascular stent grafting versus open surgical repair of descending thoracic aortic aneurysms in low-risk patients: A multicenter comparative trial 
Endovascular treatment of a combined pseudoaneurysm and arteriovenous fistula of the subclavian artery caused by a gunshot wound to the chest  Fausto.
Jennifer Chung, MD, MSc, Maral Ouzounian, MD, PhD 
Right internal thoracic artery or saphenous vein grafting
Intrinsic cardiac stem cells are essential for regeneration
Elevated messenger RNA expression and plasma protein levels of osteopontin and matrix metalloproteinase types 2 and 9 in patients with ascending aortic.
Abracadabra I, II…HeartMate 3?
Exposed thoracic aortic endovascular stent graft
Distal aortic arch aneurysm after endovascular stent graft repair for type B chronic aortic dissection  Claudio F. Russo, MD, Andrea Garatti, MD, Maurizio.
Grayson H. Wheatley, MD, FACS 
A new approach: Ischemic mitral regurgitation guidelines by and for surgeons  Patrick M. McCarthy, MD  The Journal of Thoracic and Cardiovascular Surgery 
How should we treat air leaks?
Bicuspid aortic valve aortopathy: One size fits all?
Matrix metalloproteinase and tissue inhibitor expression in atherosclerotic and nonatherosclerotic thoracic aortic aneurysms  Joseph D. Schmoker, MD,
The lord of the rings  Antonio Miceli, MD, PhD 
Temporal disparity in the induction of matrix metalloproteinases and tissue inhibitors of metalloproteinases after thoracic aortic aneurysm formation 
Gastric conduit revision after esophagectomy: The raising of Lazarus
Patient selection could be the Holy Grail of thoracic endovascular aortic repair for chronic dissecting aneurysm  Ourania Preventza, MD, Peter Chen, MD 
Support Your Specialty
An unusual case of lateral pulmonary hernia
Innovation and science: The future of valve design
Complicated acute type B aortic dissection involving the arch: Treatment by simultaneous hybrid approach under local anesthesia  Gabriele Iannelli, MD,
The assessment of cost effectiveness and the effectiveness of cost assessment in cardiothoracic surgery  Vinay Badhwar, MD  The Journal of Thoracic and.
It's not “just a shunt” but sometimes it should be…
Michele Gallo, MD, Gino Gerosa, MD 
Military surgeons just want to have fun
Surgery for aortic and mitral valve disease in the United States: A trend of change in surgical practice between 1998 and 2005  Scott D. Barnett, PhD,
Joseph A. Dearani, MD, Michael J. Ackerman, MD, PhD 
Choice of second pericardial drainage tube for posterior placement
Fenton H. McCarthy, MD, MS, Nimesh D. Desai, MD, PhD 
Sinus of Valsalva aneurysms: Stabilizing the repair destabilizing the aortic valve?  M. Sertaç Çiçek, MD, FACC  The Journal of Thoracic and Cardiovascular.
A novel technique of antegrade transapical arch and thoracic aortic endovascular repair with a triple-barrel graft  Robert Shahverdyan, MD, Navid Madershahian,
Replicating the success of mitral valve repair in the aortic valve
A fate worse than death  Jennifer S. Lawton, MD 
We are the company we keep: The importance of the tumor microenvironment  Sai Yendamuri, MD, FACS  The Journal of Thoracic and Cardiovascular Surgery 
Endovascular treatment of right-sided subclavian artery aneurysm in a congenitally malformed aortic arch  Gabriele Iannelli, MD, Luigi Di Tommaso, MD,
Passing the torch The Journal of Thoracic and Cardiovascular Surgery
Patrick T. Roughneen, MD, Grant T. Fankhauser, MD, Abe DeAnda, MD 
Warfarin or aspirin after mitral valve repair: Why work harder?
Intramuscular hemangioma of the chest wall: An unusual tumor
Hans-Joachim Schäfers, MD 
The origins of open heart surgery at the University of Minnesota 1951 to 1956  Richard A. DeWall, MD  The Journal of Thoracic and Cardiovascular Surgery 
Thoracic aortic emergencies: impact of endovascular surgery
Nitroglycerin to control blood pressure during endovascular stent-grafting of descending thoracic aortic aneurysms  Emanuel O. Bernard, MD, Edith R. Schmid,
The Journal of Thoracic and Cardiovascular Surgery
Discussion The Journal of Thoracic and Cardiovascular Surgery
Tissue valve, nitinol stent, or storage solution
The future of cardiac surgery training: A survival guide
Open repair of a new aneurysm of the thoracoabdominal aorta after endovascular stent placement  Siyamek Neragi-Miandoab, MD, James Tuchak, MD, Mamdouh.
External tracheal stenting for pediatric airway obstruction: A word of caution  Roosevelt Bryant, MD  The Journal of Thoracic and Cardiovascular Surgery 
When should the elephant (frozen elephant trunk) enter the room (aorta)?  Frank A. Baciewicz, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume.
Ralph E. Delius, MD  The Journal of Thoracic and Cardiovascular Surgery 
The Journal of Thoracic and Cardiovascular Surgery
“The more things change…”: The challenges ahead
Toward a more rational approach in treating type B aortic dissection
Ryan R. Davies, MD  The Journal of Thoracic and Cardiovascular Surgery 
Apples remain apples NO matter what
Respect the aorta The Journal of Thoracic and Cardiovascular Surgery
Preoperative PFTs: The answer is blowing in the wind
Perioperative renal function and thoracoabdominal aneurysm repair: Where do we go from here?  Leonard N. Girardi, MD  The Journal of Thoracic and Cardiovascular.
Of mice and men… The Journal of Thoracic and Cardiovascular Surgery
Grant T. Fankhauser, MD, Abe DeAnda, MD, Patrick T. Roughneen, MD 
Journal changes and initiatives
Descending thoracic and thoracoabdominal aortic aneurysms: “Busted”
Zone zero thoracic endovascular aortic repair is all about “location, location, location”  Kevin L. Greason, MD  The Journal of Thoracic and Cardiovascular.
Calpain inhibitors: The aspirin of the 21st century?
Presentation transcript:

Response of plasma matrix metalloproteinases and tissue inhibitor of metalloproteinases to stent-graft surgery for descending thoracic aortic aneurysms  Mario Monaco, MD, Paolo Stassano, MD, Luigi Di Tommaso, MD, Gabriele Iannelli, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 134, Issue 4, Pages 925-931 (October 2007) DOI: 10.1016/j.jtcvs.2007.05.044 Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 MMP-3 plasma value concentrations before and during follow-up after stent-graft placement. *Not significant; †<.05; ‡<.01; §<.001. EVAR, Endovascular aneurysm repair; MMP, matrix metalloproteinase. The Journal of Thoracic and Cardiovascular Surgery 2007 134, 925-931DOI: (10.1016/j.jtcvs.2007.05.044) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 MMP-9 plasma value concentrations before and during follow-up after stent-graft placement. *Not significant; †<.05; ‡<.01; §<.001. EVAR, Endovascular aneurysm repair; MMP, matrix metalloproteinase. The Journal of Thoracic and Cardiovascular Surgery 2007 134, 925-931DOI: (10.1016/j.jtcvs.2007.05.044) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 TIMP-1 plasma value concentrations before and during follow-up after stent-graft placement. *Not significant; †<.05; ‡<.01; §<.001. EVAR, Endovascular aneurysm repair; TIMP, tissue inhibitor of metalloproteinases. The Journal of Thoracic and Cardiovascular Surgery 2007 134, 925-931DOI: (10.1016/j.jtcvs.2007.05.044) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 MMP-9/TIMP-1 ratio before and during follow-up after stent-graft placement. *Not significant; †<.05; ‡<.01; §<.001. EVAR, Endovascular aneurysm repair; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinases. The Journal of Thoracic and Cardiovascular Surgery 2007 134, 925-931DOI: (10.1016/j.jtcvs.2007.05.044) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions